All Outputs (3)

Wnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approaches (2016)
Journal Article

Over the past few years, microRNAs (miRNAs) have not only emerged as integral regulators of gene expression at the post-transcriptional level but also respond to signalling molecules to affect cell function(s). miRNAs crosstalk with a variety of the... Read More about Wnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approaches.

Spheroid-Formation (Colonosphere) Assay for in Vitro Assessment and Expansion of Stem Cells in Colon Cancer (2016)
Journal Article

Colorectal cancers (CRCs) form a disorganized hierarchy of heterogeneous cell populations on which current chemotherapy regimens fail to exert their distinctive cytotoxicity. A small sub-population of poorly differentiated cancer stem-like cells (CSC... Read More about Spheroid-Formation (Colonosphere) Assay for in Vitro Assessment and Expansion of Stem Cells in Colon Cancer.

Fbxw7-associated drug resistance is reversed by induction of terminal differentiation in murine intestinal organoid culture (2016)
Journal Article

Colorectal cancer (CRC) is one of the top three cancer-related causes of death worldwide. FBXW7 is a known tumor-suppressor gene, commonly mutated in CRC and in a variety of other epithelial tumors. Low expression of FBXW7 is also associated with poo... Read More about Fbxw7-associated drug resistance is reversed by induction of terminal differentiation in murine intestinal organoid culture.