New Strigolactone Analogs as Plant Hormones with Low Activities in the Rhizosphere

Boyer, Fran�ois Didier; de Saint Germain, Alexandre; Pouvreau, Jean-Bernard; Clav�, Guillaume; Pillot, Jean-Paul; Roux, Am�lie; Rasmussen, Amanda; Depuydt, Stephen; Lauressergues, Dominique; Frei dit Frey, Nicolas; Heugebaert, Thomas S.S.; Stevens, Christian V.; Geelen, Danny; Goormachtig, Sofie; Rameau, Catherine

Abstract

Strigolactones (SLs) are known not only as plant hormones, but also as rhizosphere signals for establishing symbiotic and parasitic interactions. The design of new specific SL analogs is a challenging goal in understanding the basic plant biology and is also useful to control plant architectures without favoring the development of parasitic plants. Two different molecules (23 (3?-methyl-GR24), 31 (thia-3?-methyl-debranone-like molecule)) already described, and a new one (AR36), for which the synthesis is presented, are biologically compared with the well-known GR24 and the recently identified CISA-1. These different structures emphasize the wide range of parts attached to the D-ring for the bioactivity as a plant hormone. These new compounds possess a common dimethylbutenolide motif but their structure varies in the ABC part of the molecules: 23 has the same ABC part as GR24, while 31 and AR36 carry, respectively, an aromatic ring and an acyclic carbon chain. Detailed information is given for the bioactivity of such derivatives in strigolactone synthesis or in perception mutant plants (pea rms1 and rms4, Arabidopsis max2 and, max4) for different hormonal functions along with their action in the rhizosphere on arbuscular mycorrhizal hyphal growth and parasitic weed germination.

Citation

Boyer, F. D., de Saint Germain, A., Pouvreau, J., Clavé, G., Pillot, J., Roux, A., …Rameau, C. (2014). New Strigolactone Analogs as Plant Hormones with Low Activities in the Rhizosphere. Molecular Plant, 7(4), 675-690. https://doi.org/10.1093/mp/sst163

• Journal Article Type: Article
• Acceptance Date: Nov 6, 2013
• Online Publication Date: Jan 5, 2015
• Publication Date: Apr 1, 2014
• Deposit Date: Jan 25, 2017
• Publicly Available Date: Jan 25, 2017
• Journal: Molecular Plant
• Print ISSN: 1674-2052
• Electronic ISSN: 1752-9867
• Publisher: Oxford University Press
• Peer Reviewed: Peer Reviewed
• Volume: 7
• Issue: 4
• Pages: 675-690
• DOI: https://doi.org/10.1093/mp/sst163
• Keywords: strigolactones; synthetic analogs; Pisum sativum; Arabidopsis; root parasitic plants; Gigaspora rosea; plant growth regulator
• Public URL: https://nottingham-repository.worktribe.com/output/996220
• Publisher URL: http://www.sciencedirect.com/science/article/pii/S1674205214606730