Physical activity interventions in children and young people with Type 1 diabetes mellitus: a systematic review with meta-analysis

Quirk, H.; Blake, H.; Tennyson, R.; Randell, T.L.; Glazebrook, C.

Abstract

© 2014 The Authors. Aim: To synthesize evidence from randomized and non-randomized studies of physical activity interventions in children and young people with Type 1 diabetes so as to explore clinically relevant health outcomes and inform the promotion of physical activity. Method: We conducted a search of CINAHL Plus, the Cochrane Library, EMBASE, MEDLINE, PsycINFO, SCOPUS, SportDiscus and Web of Science between October and December 2012. Eligible articles included subjects aged ≤18 years with Type 1 diabetes and a physical activity intervention that was more than a one-offactivity session. Physiological, psychological, behavioural or social outcomes were those of interest. Results: A total of 26 articles (10 randomized and 16 non-randomized studies), published in the period 1964-2012, were reviewed. Although there was heterogeneity in study design, methods and reporting, 23 articles reported at least one significant beneficial health outcome at follow-up. Meta-analyses of these studies showed potential benefits of physical activity on HbA1c (11 studies, 345 participants, standardized mean difference -0.52, 95% CI -0.97 to -0.07; P = 0.02), BMI (four studies, 195 participants, standardized mean difference -0.41, 95% CI -0.70 to -0.12; P = 0.006) and triglycerides (five studies, 206 participants, standardized mean difference -0.70, 95% CI -1.25 to -0.14; P = 0.01).The largest effect size was for total cholesterol (five studies, 206 participants, standardized mean difference -0.91, 95% CI -1.66 to -0.17; P = 0.02). Conclusions: Physical activity is important for diabetes management and has the potential to delay cardiovascular disease, but there is a lack of studies that are underpinned by psychological behaviour change theory, promoting sustained physical activity and exploring psychological outcomes. There remains a lack of knowledge of how to promote physical activity in people with Type 1 diabetes.

Citation

Quirk, H., Blake, H., Tennyson, R., Randell, T., & Glazebrook, C. (2014). Physical activity interventions in children and young people with Type 1 diabetes mellitus: a systematic review with meta-analysis. Diabetic Medicine, 31(10), 1163-1173. https://doi.org/10.1111/dme.12531

• Journal Article Type: Article
• Acceptance Date: Jun 20, 2014
• Online Publication Date: Sep 16, 2014
• Publication Date: Oct 1, 2014
• Deposit Date: Nov 28, 2016
• Publicly Available Date: Nov 28, 2016
• Journal: Diabetic Medicine
• Print ISSN: 0742-3071
• Electronic ISSN: 1464-5491
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 31
• Issue: 10
• Pages: 1163-1173
• DOI: https://doi.org/10.1111/dme.12531
• Public URL: https://nottingham-repository.worktribe.com/output/994336
• Publisher URL: https://onlinelibrary.wiley.com/doi/abs/10.1111/dme.12531
• Contract Date: Nov 28, 2016