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A gyral coordinate system predictive of fibre orientations

Cottaar, Michiel; Bastiani, Matteo; Chen, Charles; Dikranian, Krikor; Van Essen, David; Behrens, Timothy E.; Sotiropoulos, Stamatios N.; Jbabdi, Saad

Authors

Michiel Cottaar

Matteo Bastiani

Charles Chen

Krikor Dikranian

David Van Essen

Timothy E. Behrens

Stamatios N. Sotiropoulos

Saad Jbabdi

Abstract

When axonal fibres approach or leave the cortex, their trajectories tend to closely follow the cortical convolutions. To quantify this tendency, we propose a three-dimensional coordinate system based on the gyral geometry. For every voxel in the brain, we define a “radial” axis orthogonal to nearby surfaces, a “sulcal” axis along the sulcal depth gradient that preferentially points from deep white matter to the gyral crown, and a “gyral” axis aligned with the long axis of the gyrus.

When compared with high-resolution, in-vivo diffusion MRI data from the Human Connectome Project, we find that in superficial white matter the apparent diffusion coefficient (at b = 1000) along the sulcal axis is on average 16% larger than along the gyral axis and twice as large as along the radial axis. This is reflected in the vast majority of observed fibre orientations lying close to the tangential plane (median angular offset 

Journal Article Type Article
Publication Date Aug 1, 2018
Journal NeuroImage
Print ISSN 1053-8119
Electronic ISSN 1095-9572
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 176
DOI https://doi.org/10.1016/j.neuroimage.2018.04.040
Publisher URL https://www.sciencedirect.com/science/article/pii/S1053811918303501
Copyright Statement Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc-nd/4.0




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