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Therapeutic cannabinoids in multiple sclerosis: immunomodulation revisited

Constantinescu, Cris S.; Gershkovich, Pavel

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Authors

Cris S. Constantinescu



Abstract

Cannabinoids are compounds with pleiotropic properties that act on the cannabinoid receptors, CB1 and CB2, and are divided into endocannabinoids, the endogenous ligands of these receptors, synthetic cannabinoids and phytocannabinoids. The latter are derived from the plant Cannabis sativa. The therapeutic and psychoactive properties of this plant have been observed and used for centuries. Of the over 60 compounds that are unique to Cannabis sativa, the substances that have been attributed the greatest therapeutic potential are Δ9‐ tetrahydrocannabinol (THC) and cannabidiol (CBD), both of which, used alone or combined with each other, have become approved drugs.

Citation

Constantinescu, C. S., & Gershkovich, P. (2018). Therapeutic cannabinoids in multiple sclerosis: immunomodulation revisited. European Journal of Neurology, 25(7), 905-906. https://doi.org/10.1111/ene.13658

Journal Article Type Article
Acceptance Date Apr 5, 2018
Online Publication Date Apr 10, 2018
Publication Date Jul 1, 2018
Deposit Date Apr 9, 2018
Publicly Available Date Apr 11, 2019
Journal European Journal of Neurology
Print ISSN 1351-5101
Electronic ISSN 1468-1331
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 25
Issue 7
Pages 905-906
DOI https://doi.org/10.1111/ene.13658
Public URL https://nottingham-repository.worktribe.com/output/943329
Publisher URL https://onlinelibrary.wiley.com/doi/abs/10.1111/ene.13658
Additional Information This is the peer reviewed version of the following article, which has been published in final form at https://onlinelibrary.wiley.com/doi/abs/10.1111/ene.13658. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Contract Date Apr 9, 2018

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