Anti-confocal assessment of middle ear inflammation

Jung, David S.; Crowe, John A.; Birchall, John P.; Somekh, Michael G.; See, Chung W.

Abstract

To improve the diagnostic prediction of recurrence of otitis media with effusion after surgery, an anti-confocal system combined with spectroscopic measurements is proposed to reject unwanted signals from the eardrum and assess the blood content. The anti-confocal system was experimentally evaluated on both optical middle ear phantom and human skin. Results showed effective rejection of signals from the eardrum using a central stop replacing the confocal pinhole, while still detecting signals from the middle ear mucosa. The system is sensitive to changes in blood content, but scattering and absorption characteristics of the eardrum can distort the measurement. Confocal detection of eardrum properties was shown to be a promising approach to correct measurements.

Citation

Jung, D. S., Crowe, J. A., Birchall, J. P., Somekh, M. G., & See, C. W. (2016). Anti-confocal assessment of middle ear inflammation. Biomedical Optics Express, 8(1), https://doi.org/10.1364/BOE.8.000230

• Journal Article Type: Article
• Acceptance Date: Nov 4, 2016
• Publication Date: Dec 12, 2016
• Deposit Date: Feb 14, 2017
• Publicly Available Date: Feb 14, 2017
• Journal: Biomedical Optics Express
• Electronic ISSN: 2156-7085
• Publisher: Optical Society of America
• Peer Reviewed: Peer Reviewed
• Volume: 8
• Issue: 1
• DOI: https://doi.org/10.1364/BOE.8.000230
• Keywords: Confocal microscopy, Medical and biological imaging, Otolaryngology, Imaging through turbid media
• Public URL: https://nottingham-repository.worktribe.com/output/835553
• Publisher URL: http://dx.doi.org/10.1364/BOE.8.000230