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Anti-confocal assessment of middle ear inflammation

Jung, David S.; Crowe, John A.; Birchall, John P.; Somekh, Michael G.; See, Chung W.

Authors

David S. Jung david.jung@nottingham.ac.uk

John A. Crowe John.Crowe@nottingham.ac.uk

John P. Birchall

Michael G. Somekh

Chung W. See



Abstract

To improve the diagnostic prediction of recurrence of otitis media with effusion after surgery, an anti-confocal system combined with spectroscopic measurements is proposed to reject unwanted signals from the eardrum and assess the blood content. The anti-confocal system was experimentally evaluated on both optical middle ear phantom and human skin. Results showed effective rejection of signals from the eardrum using a central stop replacing the confocal pinhole, while still detecting signals from the middle ear mucosa. The system is sensitive to changes in blood content, but scattering and absorption characteristics of the eardrum can distort the measurement. Confocal detection of eardrum properties was shown to be a promising approach to correct measurements.

Journal Article Type Article
Publication Date Dec 12, 2016
Journal Biomedical Optics Express
Electronic ISSN 2156-7085
Publisher Optical Society of America
Peer Reviewed Peer Reviewed
Volume 8
Issue 1
APA6 Citation Jung, D. S., Crowe, J. A., Birchall, J. P., Somekh, M. G., & See, C. W. (2016). Anti-confocal assessment of middle ear inflammation. Biomedical Optics Express, 8(1), https://doi.org/10.1364/BOE.8.000230
DOI https://doi.org/10.1364/BOE.8.000230
Keywords Confocal microscopy, Medical and biological imaging, Otolaryngology, Imaging through turbid media
Publisher URL http://dx.doi.org/10.1364/BOE.8.000230
Copyright Statement Copyright information regarding this work can be found at the following address: http://eprints.nottingh.../end_user_agreement.pdf

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf





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