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A novel approach to design lesion-specific stents for minimum recoil

Farhan Khan, Muhammad; Brackett, David; Ashcroft, Ian; Tuck, Christopher; Wildman, Ricky D.

Authors

Muhammad Farhan Khan

David Brackett

IAN ASHCROFT Ian.Ashcroft@nottingham.ac.uk
Professorof Mechanics of Solids

RICKY WILDMAN Ricky.Wildman@nottingham.ac.uk
Professor of Multiphase Flow and Mechanics



Abstract

Stent geometries are obtained by topology optimization for minimized compliance under different stenosis levels and plaque material types. Three levels of stenosis by cross-sectional area, i.e., 30%, 40%, and 50% and three different plaque material properties, i.e., calcified, cellular, and hypocellular, were studied. The raw optimization results were converted to clear design concepts and their performance was evaluated by implanting them in their respective stenosed artery types using finite element analysis. The results were compared with a generic stent in similar arteries, which showed that the new designs showed less recoil. This work provides a concept that stents could be tailored to specific lesions in order to minimize recoil and maintain a patent lumen in stenotic arteries.

Citation

Farhan Khan, M., Brackett, D., Ashcroft, I., Tuck, C., & Wildman, R. D. (in press). A novel approach to design lesion-specific stents for minimum recoil. Journal of Medical Devices, 11(1), https://doi.org/10.1115/1.4034880

Journal Article Type Article
Acceptance Date Aug 30, 2016
Online Publication Date Dec 21, 2016
Deposit Date Feb 14, 2017
Publicly Available Date Feb 14, 2017
Journal Journal of Medical Devices
Print ISSN 1932-6181
Electronic ISSN 1932-619X
Publisher American Society of Mechanical Engineers
Peer Reviewed Peer Reviewed
Volume 11
Issue 1
Article Number 011001
DOI https://doi.org/10.1115/1.4034880
Public URL http://eprints.nottingham.ac.uk/id/eprint/40579
Publisher URL http://medicaldevices.asmedigitalcollection.asme.org/article.aspx?articleid=2565891
Copyright Statement Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf

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Inst-Rep-MED-15-1278 - A Novel Approach to Design Lesion-Specific Stents for Minimum Recoil.pdf (1.9 Mb)
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Copyright Statement
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf





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