A novel approach to design lesion-specific stents for minimum recoil

Farhan Khan, Muhammad; Brackett, David; Ashcroft, Ian; Tuck, Christopher; Wildman, Ricky D.

Abstract

Stent geometries are obtained by topology optimization for minimized compliance under different stenosis levels and plaque material types. Three levels of stenosis by cross-sectional area, i.e., 30%, 40%, and 50% and three different plaque material properties, i.e., calcified, cellular, and hypocellular, were studied. The raw optimization results were converted to clear design concepts and their performance was evaluated by implanting them in their respective stenosed artery types using finite element analysis. The results were compared with a generic stent in similar arteries, which showed that the new designs showed less recoil. This work provides a concept that stents could be tailored to specific lesions in order to minimize recoil and maintain a patent lumen in stenotic arteries.

Citation

Farhan Khan, M., Brackett, D., Ashcroft, I., Tuck, C., & Wildman, R. D. (in press). A novel approach to design lesion-specific stents for minimum recoil. Journal of Medical Devices, 11(1), Article 011001. https://doi.org/10.1115/1.4034880

• Journal Article Type: Article
• Acceptance Date: Aug 30, 2016
• Online Publication Date: Dec 21, 2016
• Deposit Date: Feb 14, 2017
• Publicly Available Date: Feb 14, 2017
• Journal: Journal of Medical Devices
• Print ISSN: 1932-6181
• Electronic ISSN: 1932-619X
• Publisher: American Society of Mechanical Engineers
• Peer Reviewed: Peer Reviewed
• Volume: 11
• Issue: 1
• Article Number: 011001
• DOI: https://doi.org/10.1115/1.4034880
• Public URL: https://nottingham-repository.worktribe.com/output/832596
• Publisher URL: http://medicaldevices.asmedigitalcollection.asme.org/article.aspx?articleid=2565891