Developing Mn-doped lead sulfide quantum dots for MRI labels

Turyanska, Lyudmila; Moro, Fabrizio; Patan�, Amalia; Barr, James; K�ckenberger, Walter; Taylor, Alexander; Faas, Henryk; Fowler, Maxine J.; Wigmore, Peter; Trueman, Rebecca C.; Williams, Huw Edward Llewelyn; Thomas, Neil R.

Abstract

Magnetic interactions of Mn2+ions in lead sulfide (PbS) nanocrystals with protons in water are probed by NMR and MRI. A thin layer of capping molecules enables free solvent diffusion to the nanocrystal surface resulting in a decrease of proton relaxation times. Magnetic resonance imaging of neuronal cell pellets exposed to (PbMn)S at non-toxic concentrations demonstrates their prospects as MRI-labels.

• Journal Article Type: Article
• Acceptance Date: Oct 10, 2016
• Online Publication Date: Oct 10, 2016
• Publication Date: Nov 14, 2016
• Deposit Date: Oct 14, 2016
• Publicly Available Date: Oct 14, 2016
• Journal: Journal of Materials Chemistry B
• Print ISSN: 2050-750X
• Electronic ISSN: 2050-7518
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 4
• Issue: 42
• Pages: 6797-6802
• DOI: https://doi.org/10.1039/c6tb02574a
• Public URL: https://nottingham-repository.worktribe.com/output/828769
• Publisher URL: http://pubs.rsc.org/en/Content/ArticleLanding/2016/TB/C6TB02574A#!divAbstract
• Additional Information: : This document is Similarity Check deposited; : Supplementary Information; : The Royal Society of Chemistry has an exclusive publication licence for this journal; OPEN ACCESS: This article is freely available. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0); : Single-blind; : Received 2 October 2016; Accepted 10 October 2016; Accepted Manuscript published 10 October 2016; Advance Article published 17 October 2016; Version of Record published 26 October 2016