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Developing Mn-doped lead sulfide quantum dots for MRI labels

Authors

Fabrizio Moro

James Barr

Walter

Alexander Taylor

Henryk Faas

Maxine J. Fowler

Peter Wigmore

NEIL THOMAS neil.thomas@nottingham.ac.uk
Professor of Medicinal and Biological Chemistry



Abstract

Magnetic interactions of Mn2+ions in lead sulfide (PbS) nanocrystals with protons in water are probed by NMR and MRI. A thin layer of capping molecules enables free solvent diffusion to the nanocrystal surface resulting in a decrease of proton relaxation times. Magnetic resonance imaging of neuronal cell pellets exposed to (PbMn)S at non-toxic concentrations demonstrates their prospects as MRI-labels.

Citation

Turyanska, L., Moro, F., Patanè, A., Barr, J., Köckenberger, W., Taylor, A., …Thomas, N. R. (2016). Developing Mn-doped lead sulfide quantum dots for MRI labels. Journal of Materials Chemistry B, 4(42), 6797-6802. https://doi.org/10.1039/c6tb02574a

Journal Article Type Article
Acceptance Date Oct 10, 2016
Online Publication Date Oct 10, 2016
Publication Date Nov 14, 2016
Deposit Date Oct 14, 2016
Publicly Available Date Oct 14, 2016
Journal Journal of Materials Chemistry B
Print ISSN 2050-750X
Electronic ISSN 2050-7518
Publisher Royal Society of Chemistry
Peer Reviewed Peer Reviewed
Volume 4
Issue 42
Pages 6797-6802
DOI https://doi.org/10.1039/c6tb02574a
Public URL https://nottingham-repository.worktribe.com/output/828769
Publisher URL http://pubs.rsc.org/en/Content/ArticleLanding/2016/TB/C6TB02574A#!divAbstract
Additional Information : This document is Similarity Check deposited; : Supplementary Information; : The Royal Society of Chemistry has an exclusive publication licence for this journal; OPEN ACCESS: This article is freely available. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0); : Single-blind; : Received 2 October 2016; Accepted 10 October 2016; Accepted Manuscript published 10 October 2016; Advance Article published 17 October 2016; Version of Record published 26 October 2016

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0





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