Outputs (142)

PIMMS-Dash: Accessible analysis, interrogation, and visualisation of high-throughput transposon insertion sequencing (TIS) data (2024)
Journal Article
Blanchard, A. M., Taylor, A., Warry, A., Shephard, F., Curwen, A., Leigh, J. A., Emes, R. D., & Egan, S. A. (2024). PIMMS-Dash: Accessible analysis, interrogation, and visualisation of high-throughput transposon insertion sequencing (TIS) data. Computational and Structural Biotechnology Journal, 23, 3780-3783. https://doi.org/10.1016/j.csbj.2024.10.025

Motivation

Current methods for visualising and interrogating high-throughput transposon insertion mutagenesis sequencing (TIS) data requires a significant time investment in learning bioinformatics, often producing static figures that do not facil... Read More about PIMMS-Dash: Accessible analysis, interrogation, and visualisation of high-throughput transposon insertion sequencing (TIS) data.

Perceptions and Experiences of Undergraduate Students Regarding Social Media as a Tool for Government COVID-19-Related Messages: A Qualitative Study in Nottingham, UK (2023)
Journal Article
Sandhu, S., Wilson, E., & Chattopadhyay, K. (2023). Perceptions and Experiences of Undergraduate Students Regarding Social Media as a Tool for Government COVID-19-Related Messages: A Qualitative Study in Nottingham, UK. International Journal of Environmental Research and Public Health, 20(20), Article 6903. https://doi.org/10.3390/ijerph20206903

The rise of social media has given way to its use as a form of public health communication. Previous research has shown social media-based interventions to be effective, particularly for university students. Social media was used as a tool for public... Read More about Perceptions and Experiences of Undergraduate Students Regarding Social Media as a Tool for Government COVID-19-Related Messages: A Qualitative Study in Nottingham, UK.

Controlled release of MT-1207 using a novel gastroretentive bilayer system comprised of hydrophilic and hydrophobic polymers (2023)
Journal Article
Vrettos, N., Wang, P., Wang, Y., Roberts, C. J., Xu, J., Yao, H., & Zhu, Z. (2023). Controlled release of MT-1207 using a novel gastroretentive bilayer system comprised of hydrophilic and hydrophobic polymers. Pharmaceutical Development and Technology, 28(8), 724-742. https://doi.org/10.1080/10837450.2023.2238822

In the present study, novel gastroretentive bilayer tablets were developed that are promising for the once-a-day oral delivery of the drug candidate MT-1207. The gastroretentive layer consisted of a combination of hydrophilic and hydrophobic polymers... Read More about Controlled release of MT-1207 using a novel gastroretentive bilayer system comprised of hydrophilic and hydrophobic polymers.

Impacts of the COVID-19 pandemic and self-isolation on students and staff in higher education: A qualitative study (2021)
Journal Article
Knight, H., Carlisle, S., O’connor, M., Briggs, L., Fothergill, L., Al-Oraibi, A., …Blake, H. (2021). Impacts of the COVID-19 pandemic and self-isolation on students and staff in higher education: A qualitative study. International Journal of Environmental Research and Public Health, 18(20), Article 10675. https://doi.org/10.3390/ijerph182010675

This qualitative study explored the impact of COVID-19 self-isolation and social restriction measures on university students, through the perspectives of both students and the staff supporting them. The study comprised 11 focus groups (students) and... Read More about Impacts of the COVID-19 pandemic and self-isolation on students and staff in higher education: A qualitative study.

Clinicopathological and prognostic significance of Ras association and pleckstrin homology domains 1 (RAPH1) in breast cancer (2018)
Journal Article
Kurozumi, S., Joseph, C., Sonbul, S., Aleskandarany, M. A., Pigera, M., Alsaleem, M., …Rakha, E. A. (2018). Clinicopathological and prognostic significance of Ras association and pleckstrin homology domains 1 (RAPH1) in breast cancer. Breast Cancer Research and Treatment, 172(1), 61–68. https://doi.org/10.1007/s10549-018-4891-y

BACKGROUND: Ras association and pleckstrin homology domains 1 (RAPH1) is involved in cytoskeleton regulation and re-epithelialisation in invasive carcinoma and therefore may play a key role in carcinogenesis and metastasis. We herein investigated the... Read More about Clinicopathological and prognostic significance of Ras association and pleckstrin homology domains 1 (RAPH1) in breast cancer.

A randomised controlled trial of the compuLsive Exercise Activity TheraPy (LEAP): a new approach to compulsive exercise in anorexia nervosa (2018)
Journal Article
Hay, P., Touyz, S., Arcelus, J., Pike, K., Attia, E., Crosby, R. D., Madden, S., Wales, J., La Puma, M., Heriseanu, A. I., Young, S., & Meyer, C. (2018). A randomised controlled trial of the compuLsive Exercise Activity TheraPy (LEAP): a new approach to compulsive exercise in anorexia nervosa. International Journal of Eating Disorders, 51(8), 999-1004. https://doi.org/10.1002/eat.22920

Objective: To compare the efficacy of the compuLsive Exercise Activity theraPy (LEAP) programme integrated with manualised cognitive behavioural therapy for anorexia nervosa (CBT-AN) compared to CBT-AN alone.
Method: Seventy-eight adults were rando... Read More about A randomised controlled trial of the compuLsive Exercise Activity TheraPy (LEAP): a new approach to compulsive exercise in anorexia nervosa.

Refinement and validation of the Social Participation Restrictions Questionnaire: an application of Rasch analysis and traditional psychometric analysis techniques (2018)
Journal Article
Eithne, H., David, M., Johanna, B., & Melanie, F. (2019). Refinement and validation of the Social Participation Restrictions Questionnaire: an application of Rasch analysis and traditional psychometric analysis techniques. Ear and Hearing, 40(2), 328-339. https://doi.org/10.1097/AUD.0000000000000618

Objectives: The primary aim of this research was to refine and validate the Social Participation Restrictions Questionnaire (SPaRQ). The SPaRQ is a hearing-specific, patient-reported outcome measure that was originally developed through consultation... Read More about Refinement and validation of the Social Participation Restrictions Questionnaire: an application of Rasch analysis and traditional psychometric analysis techniques.

Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas (2018)
Journal Article
Geyer, F. C., Li, A., Papanastasiou, A. D., Smith, A., Selenica, P., Burke, K. A., Edelweiss, M., Wen, H.-C., Piscuoglio, S., Schultheis, A. M., Martelotto, L. G., Pareja, F., Brandes, A., Lozada, J., Macedo, G. S., de Filippo, M. R., Jungbluth, A. A., Foschini, M. P., Wen, H. Y., Brogi, E., …Reis-Filho, J. S. (2018). Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas. Nature Communications, 9, Article 1816. https://doi.org/10.1038/s41467-018-04128-5

Adenomyoepithelioma of the breast is a rare tumor characterized by epithelial-myoepithelial differentiation, of which a subset will progress to invasive or metastatic cancer. We sought to define the genomic landscape of adenomyoepitheliomas. Massivel... Read More about Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas.

Development of a multimedia educational programme for first-time hearing aid users: a participatory design (2018)
Journal Article
Ferguson, M. A., Leighton, P., Brandreth, M., & Wharrad, H. (in press). Development of a multimedia educational programme for first-time hearing aid users: a participatory design. International Journal of Audiology, https://doi.org/10.1080/14992027.2018.1457803

Objective: To develop content for a series of interactive video tutorials (or reusable learning objects, RLOs) for first-time adult hearing aid users, to enhance knowledge of hearing aids and communication.
Design: RLO content was based on an elect... Read More about Development of a multimedia educational programme for first-time hearing aid users: a participatory design.

The concept of compassion within UK media generated discourse: a corpus informed analysis (2018)
Journal Article
Bond, C., Stacey, G., Field-Richards, S., Callaghan, P., Keeley, P., Lymn, J., Redsell, S., & Spiby, H. (2018). The concept of compassion within UK media generated discourse: a corpus informed analysis. Journal of Clinical Nursing, 27(15-16), 3081-3090. https://doi.org/10.1111/jocn.14496

Aims and objectives: To examine how the concept of compassion is socially constructed within UK discourse, in response to recommendations that aspiring nurses gain care experience prior to entering nurse education.
Background: Following a report of... Read More about The concept of compassion within UK media generated discourse: a corpus informed analysis.