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The future of multiple sclerosis treatments

Coclitu, Catalina; Constantinescu, Cris S.; Tanasescu, Radu

Authors

Catalina Coclitu

Cris S. Constantinescu

Radu Tanasescu



Abstract

Introduction. There are not many conditions in which the last few decades have brought such a major change in the landscape of treatments as is the case of multiple sclerosis (MS). A number of disease modifying treatments (DMTs) are presently available for the treatment of the inflammatory phase of this disabling disease; however, the need for treating neurodegeneration and halting the progression of disability is still unmet.

Areas covered: In this paper we review the available information on existing and emerging DMTs and we discuss their place within the context of different treatment strategies in MS.

Expert Commentary: The future of MS treatments should include the development of new treatment strategies tackling disease progression, together with a better understanding of the side-effects and the best sequential strategy of implementation of available and emerging drugs.

Citation

Coclitu, C., Constantinescu, C. S., & Tanasescu, R. (in press). The future of multiple sclerosis treatments. Expert Review of Neurotherapeutics, 16(12), https://doi.org/10.1080/14737175.2016.1243056

Journal Article Type Article
Acceptance Date Sep 27, 2016
Online Publication Date Oct 21, 2016
Deposit Date Oct 19, 2016
Publicly Available Date Oct 21, 2016
Journal Expert Review of Neurotherapeutics
Print ISSN 1473-7175
Electronic ISSN 1744-8360
Publisher Taylor & Francis Open
Peer Reviewed Peer Reviewed
Volume 16
Issue 12
DOI https://doi.org/10.1080/14737175.2016.1243056
Keywords Multiple sclerosis, Immunomodulation, Monoclonal antibodies, Remyelination, Repurposing
Public URL http://eprints.nottingham.ac.uk/id/eprint/37718
Publisher URL http://www.tandfonline.com/doi/abs/10.1080/14737175.2016.1243056?journalCode=iern20
Copyright Statement Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf





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