The future of multiple sclerosis treatments
Coclitu, Catalina; Constantinescu, Cris S.; Tanasescu, Radu
Cris S. Constantinescu
Introduction. There are not many conditions in which the last few decades have brought such a major change in the landscape of treatments as is the case of multiple sclerosis (MS). A number of disease modifying treatments (DMTs) are presently available for the treatment of the inflammatory phase of this disabling disease; however, the need for treating neurodegeneration and halting the progression of disability is still unmet.
Areas covered: In this paper we review the available information on existing and emerging DMTs and we discuss their place within the context of different treatment strategies in MS.
Expert Commentary: The future of MS treatments should include the development of new treatment strategies tackling disease progression, together with a better understanding of the side-effects and the best sequential strategy of implementation of available and emerging drugs.
Coclitu, C., Constantinescu, C. S., & Tanasescu, R. (in press). The future of multiple sclerosis treatments. Expert Review of Neurotherapeutics, 16(12), https://doi.org/10.1080/14737175.2016.1243056
|Journal Article Type||Article|
|Acceptance Date||Sep 27, 2016|
|Online Publication Date||Oct 21, 2016|
|Deposit Date||Oct 19, 2016|
|Publicly Available Date||Oct 21, 2016|
|Journal||Expert Review of Neurotherapeutics|
|Publisher||Taylor & Francis Open|
|Peer Reviewed||Peer Reviewed|
|Keywords||Multiple sclerosis, Immunomodulation, Monoclonal antibodies, Remyelination, Repurposing|
|Copyright Statement||Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf|
The future of MS treatments.pdf
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf
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