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Ancient and modern DNA reveal dynamics of domestication and cross-continental dispersal of the dromedary

Almathen, Faisal; Charruau, Pauline; Mohandesan, Elmira; Mwacharo, Joram M.; Orozco-terWengel, Pablo; Pitt, Daniel; Abdussamad, Abdussamad M.; Uerpmann, Hans-Peter; Uerpmann, Margarethe; De Cupere, Bea; Magee, Peter; Alnaqeeb, Majed A.; Salim, Bashir; Raziq, Abdul; Dessie, Tadelle; Abdelhadi, Omer M.; Banabazi, Mohammad H.; Al-Eknah, Marzook; Walzer, Chris; Faye, Bernard; Hofreiter, Michael; Peters, Joris; Hanotte, Olivier; Burger, Pamela A.

Authors

Faisal Almathen

Pauline Charruau

Elmira Mohandesan

Joram M. Mwacharo

Pablo Orozco-terWengel

Daniel Pitt

Abdussamad M. Abdussamad

Hans-Peter Uerpmann

Margarethe Uerpmann

Bea De Cupere

Peter Magee

Majed A. Alnaqeeb

Bashir Salim

Abdul Raziq

Tadelle Dessie

Omer M. Abdelhadi

Mohammad H. Banabazi

Marzook Al-Eknah

Chris Walzer

Bernard Faye

Michael Hofreiter

Joris Peters

OLIVIER HANOTTE OLIVIER.HANOTTE@NOTTINGHAM.AC.UK
Director of Frozen Ark Project & Professor of Genetics & Conservation

Pamela A. Burger



Abstract

Dromedaries have been fundamental to the development of human societies in arid landscapes and for long-distance trade across hostile hot terrains for 3,000 y. Today they continue to be an important livestock resource in marginal agro-ecological zones. However, the history of dromedary domestication and the influence of ancient trading networks on their genetic structure have remained elusive. We combined ancient DNA sequences of wild and early-domesticated dromedary samples from arid regions with nuclear microsatellite and mitochondrial genotype information from 1,083 extant animals collected across the species’ range. We observe little phylogeographic signal in the modern population, indicative of extensive gene flow and virtually affecting all regions except East Africa, where dromedary populations have remained relatively isolated. In agreement with archaeological findings, we identify wild dromedaries from the southeast Arabian Peninsula among the founders of the domestic dromedary gene pool. Approximate Bayesian computations further support the “restocking from the wild” hypothesis, with an initial domestication followed by introgression from individuals from wild, now-extinct populations. Compared with other livestock, which show a long history of gene flow with their wild ancestors, we find a high initial diversity relative to the native distribution of the wild ancestor on the Arabian Peninsula and to the brief coexistence of early-domesticated and wild individuals. This study also demonstrates the potential to retrieve ancient DNA sequences from osseous remains excavated in hot and dry desert environments.

Citation

Almathen, F., Charruau, P., Mohandesan, E., Mwacharo, J. M., Orozco-terWengel, P., Pitt, D., …Burger, P. A. (2016). Ancient and modern DNA reveal dynamics of domestication and cross-continental dispersal of the dromedary. Proceedings of the National Academy of Sciences, 113(24), https://doi.org/10.1073/pnas.1519508113

Journal Article Type Article
Acceptance Date Apr 4, 2016
Publication Date Jun 14, 2016
Deposit Date Jun 30, 2016
Publicly Available Date Jun 30, 2016
Journal Proceedings of the National Academy of Sciences
Print ISSN 0027-8424
Electronic ISSN 1091-6490
Publisher National Academy of Sciences
Peer Reviewed Peer Reviewed
Volume 113
Issue 24
DOI https://doi.org/10.1073/pnas.1519508113
Public URL http://eprints.nottingham.ac.uk/id/eprint/34506
Publisher URL http://www.pnas.org/content/113/24/6707
Copyright Statement Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf





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