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α-chloralose poisoning in a cat

Grau-Roma, Llorenç; Stephens, Adam; Wessmann, Annette; Carmichael, Nick; de Brot, Simone

Authors

Llorenç Grau-Roma llorenc.grau@nottingham.ac.uk

Adam Stephens svyas2@nottingham.ac.uk

Annette Wessmann annettewessmann@scarsdalevets.com

Nick Carmichael nickcarmichael9876@gmail.com

Simone de Brot simone.debrot@nottingham.ac.uk



Abstract

A five-year-old domestic cat with acute unexplainable neurological signs was presented for postmortem examination. Clinically, the cat showed an acute onset of ataxia, depressed mentation and continuous twitching/ seizure activity in the morning after having been outside overnight. Despite immediate treatment, the cat# progressed within 24 hours to a comatose state, opisthotonus and severe miosis unresponsive to light. Given a poor prognosis, euthanasia was elected. Gross findings were disappointing and consisted of a nonspecific lung oedema and congested lungs and spleen. Surprisingly, within the stomach and intestines, fragments of cockshafers were found. Histological examination confirmed the gross findings and additionally showed evidence of mild brain oedema, but failed to identify a cause for the severe clinical signs. In a final attempt to solve the case, a urine sample was tested for toxic substances and it was found to contain a significant amount of α-chloralose. This finding was unexpected.

Citation

Grau-Roma, L., Stephens, A., Wessmann, A., Carmichael, N., & de Brot, S. (2016). α-chloralose poisoning in a cat. https://doi.org/10.1136/vetreccr-2016-000313

Journal Article Type Article
Acceptance Date Apr 24, 2016
Publication Date May 17, 2016
Deposit Date Oct 31, 2016
Publicly Available Date Oct 31, 2016
Journal Veterinary Record Case Reports
Electronic ISSN 2052-6121
Publisher BMJ Publishing Group
Peer Reviewed Peer Reviewed
Volume 4
Issue e00031
DOI https://doi.org/10.1136/vetreccr-2016-000313
Public URL http://eprints.nottingham.ac.uk/id/eprint/37339
Publisher URL http://vetrecordcasereports.bmj.com/content/4/1/e000313
Copyright Statement Copyright information regarding this work can be found at the following address: http://eprints.nottingh.../end_user_agreement.pdf

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf





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