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The changing vaccine landscape: rates of COVID-19 vaccine acceptance and hesitancy in young adults during vaccine rollout

Knight, H.; Jia, R.; Ayling, K.; Blake, H.; Morling, J. R.; Villalon, A. M.; Corner, J.; Denning, C.; Ball, J.; Bolton, K.; Figueredo, G.; Morris, D.; Tighe, P.; Vedhara, K.

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Authors

HOLLY KNIGHT HOLLY.KNIGHT@NOTTINGHAM.AC.UK
Senior Research Fellow

R. Jia

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HOLLY BLAKE holly.blake@nottingham.ac.uk
Professor of Behavioural Medicine

JOANNE MORLING JOANNE.MORLING@NOTTINGHAM.AC.UK
Clinical Associate Professor

J. Corner

CHRIS DENNING chris.denning@nottingham.ac.uk
Professor of Stem Cell Biology

JONATHAN BALL jonathan.ball@nottingham.ac.uk
Professor of Molecular Virology

PATRICK TIGHE paddy.tighe@nottingham.ac.uk
Professor of Molecular Immunology

K. Vedhara



Abstract

Aims: Development and rollout of vaccines offers the best opportunity for population protection against the SARS-CoV-2 (COVID-19) virus. However, hesitancy towards the vaccines might impede successful uptake in the United Kingdom, particularly in young adults who demonstrate the highest rates of hesitancy. This prospective study explored COVID-19 vaccine hesitancy in young adults and whether the reasons behind these attitudes changed during the initial stages of the United Kingdom’s vaccine rollout. Method: Data on vaccination intention were collected from a British university student cohort at three time points: October 2020, February 2021, and March 2021. This online survey included items on intention to receive a vaccine and a free-text response for the reasons behind this intention. Cochran’s Q tests examined changes in rates of hesitancy and acceptance over time and free-text responses were analysed thematically. Results: At baseline, 893 students provided data, with 476 participants completing all three time points. Hesitancy declined over time, with 29.4% of participants expressing hesitancy at baseline, reducing to 9.1% at wave 2 and 5.9% at wave 3. The most commonly endorsed themes for those willing to accept a vaccine were self-protection against COVID-19 and pro-social reasons, including protecting the population or unspecific others, and ending the pandemic/returning to normal life. The most commonly endorsed hesitancy themes related to ‘confidence’ in the vaccines and potential personal risk, including insufficient testing/scientific evidence, concern about side effects, and long-term effects. These reasons remained the most commonly endorsed at both waves 2 and 3. Conclusions: While a decline in hesitancy was observed over time, the key reasons behind both vaccine acceptance and hesitancy remained consistent. Reasons behind hesitancy aligned with those of the general public, providing support for the use of generalist interventions. Pro-social reasons frequently underpinned vaccine acceptance, so cohort-specific interventions targeting those factors may be of benefit.

Citation

Knight, H., Jia, R., Ayling, K., Blake, H., Morling, J. R., Villalon, A. M., …Vedhara, K. (2023). The changing vaccine landscape: rates of COVID-19 vaccine acceptance and hesitancy in young adults during vaccine rollout. Perspectives in Public Health, 143(4), 220-224. https://doi.org/10.1177/17579139221094750

Journal Article Type Article
Acceptance Date Mar 30, 2022
Online Publication Date May 15, 2022
Publication Date 2023-07
Deposit Date Apr 10, 2022
Publicly Available Date May 15, 2022
Journal Perspectives in Public Health
Print ISSN 1757-9139
Electronic ISSN 1757-9147
Publisher SAGE Publications
Peer Reviewed Peer Reviewed
Volume 143
Issue 4
Pages 220-224
DOI https://doi.org/10.1177/17579139221094750
Keywords COVID-19, vaccine hesitancy, public health
Public URL https://nottingham-repository.worktribe.com/output/7754609
Publisher URL https://journals.sagepub.com/doi/10.1177/17579139221094750