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Group-based memory rehabilitation for people with multiple sclerosis: Subgroup analysis of the remind trial

Kneebone, Ian; Martin, Kristy Jane; Lincoln, Nadina; Das Nair, Roshan

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Ian Kneebone

Kristy Jane Martin

Nadina Lincoln

Professor of Clinical Psychology and Neuropsychology


© 2014 MA Healthcare Ltd. Background/Aim: Memory problems are frequently reported in people with multiple sclerosis (MS). These can be debilitating and affect individuals and their families. This subgroup analysis focused on the effectiveness of memory rehabilitation in patients with MS.Methods: Data were extracted from a single-blind randomised controlled trial, the ReMiND trial, which also included participants with traumatic brain injury and stroke. Participants were randomly allocated to compensation or restitution treatment programmes, or a self-help control. The programmes were manual-based and comprised two individual sessions and ten group sessions. Outcome measures included assessments of memory, mood and activities of daily living. A total of 39 patients with MS participated in this study (ten males (26%), 29 females (74%); mean±SD age: 48.3±10.8 years).Results: Comparison of groups showed no significant effect of treatment on memory, but there were significant differences between compensation and restitution on self-report symptoms of emotional distress at both five-(p=0.04) and seven-month (p=0.05) follow-up sessions. The compensation group showed less distress than the restitution group.Conclusions: Individuals with MS who received compensation memory rehabilitation reported significantly less emotional distress than those who received restitution. Further research is needed to explore why self-reported memory problems did not differ between groups.

Journal Article Type Article
Acceptance Date Oct 24, 2014
Online Publication Date Dec 3, 2014
Publication Date Dec 2, 2014
Deposit Date Jun 11, 2015
Publicly Available Date Jun 11, 2015
Journal International Journal of Therapy and Rehabilitation
Print ISSN 1741-1645
Electronic ISSN 1759-779X
Publisher Mark Allen Healthcare
Peer Reviewed Peer Reviewed
Volume 21
Issue 12
Pages 590-596
Keywords Multiple sclerosis, Memory, Rehabilitation, Randomised controlled trial
Public URL
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