Rate of improvement of CF life expectancy exceeds that of general population: observational death registration study

Hurley, Matthew; McKeever, Tricia M.; Prayle, Andrew P.; Smyth, Alan R.; Fogarty, Andrew W.

Abstract

Background: It is unclear why cystic fibrosis (CF) survival has improved. We wished to quantify increases in CF median age of death in the context of general population survival improvement.
Method: Death registration data analysis (US, England & Wales (E&W)—1972–2009).
Results: CF median age of death is higher in US than E&W and greater for males, opposite to that of death from all causes. CF median age of death has increased by 0.543 life years per year (E&W, US combined (95% confidence interval 0.506, 0.582)). The difference in median age at death between those dying from all causes and CF decreased in both territories. CF median age of death for males is greater than for females in both territories. This gap has not narrowed.
Conclusion: The median age of death of people with CF is improving more rapidly than that of the general population in US and E&W.

Citation

Hurley, M., McKeever, T. M., Prayle, A. P., Smyth, A. R., & Fogarty, A. W. (2014). Rate of improvement of CF life expectancy exceeds that of general population: observational death registration study. Journal of Cystic Fibrosis, 13(4), https://doi.org/10.1016/j.jcf.2013.12.002

• Journal Article Type: Article
• Acceptance Date: Sep 20, 2013
• Online Publication Date: Jan 10, 2014
• Publication Date: Jul 1, 2014
• Deposit Date: Feb 15, 2016
• Publicly Available Date: Feb 15, 2016
• Journal: Journal of Cystic Fibrosis
• Print ISSN: 1569-1993
• Electronic ISSN: 1873-5010
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 13
• Issue: 4
• DOI: https://doi.org/10.1016/j.jcf.2013.12.002
• Keywords: Cystic fibrosis; Survival; Mortality; Healthcare
• Public URL: https://nottingham-repository.worktribe.com/output/729617
• Publisher URL: http://www.sciencedirect.com/science/article/pii/S1569199313002270
• Contract Date: Feb 15, 2016