Oxidation state of a polyurethane membrane after plasma etching

Moles, Matthew D.; Scotchford, Colin A.; Campbell Ritchie, Alastair

Abstract

Low moduli cell culture substrates can be used to apply dynamic mechanical strain to cells, by surface deformation. Understanding the surface interaction with cells is critical to improving cell adhesion and normal growth. A medical grade polyurethane (PU), Chronoflex AL 80A, was modified by oxygen plasma etching and characterised by X-ray photoelectron spectroscopy. Etching resulted in increased cross-linking at the isocyanate bond and formation of new oxygen moieties. The model, derived from patent data and XPS data of the unetched PU, indicated that the additional oxygen was likely to be hydroxyl and carbonyl groups. Etched membranes enhanced protein adhesion, resulting in full surface coverage compared to unetched PU. The etched PU supported cell adhesion and spreading, while the unetched PU was not conducive to monolayer formation.

Citation

Moles, M. D., Scotchford, C. A., & Campbell Ritchie, A. (2014). Oxidation state of a polyurethane membrane after plasma etching. 00 Journal not listed, 2014, Article 347979. https://doi.org/10.1155/2014/347979

• Journal Article Type: Article
• Acceptance Date: Feb 24, 2014
• Online Publication Date: Apr 8, 2014
• Publication Date: Apr 8, 2014
• Deposit Date: Aug 23, 2017
• Publicly Available Date: Aug 23, 2017
• Journal: Conference Papers in Science
• Electronic ISSN: 2356-6108
• Peer Reviewed: Peer Reviewed
• Volume: 2014
• Article Number: 347979
• DOI: https://doi.org/10.1155/2014/347979
• Public URL: https://nottingham-repository.worktribe.com/output/727364
• Publisher URL: https://www.hindawi.com/archive/2014/347979/
• Additional Information: This Conference Paper is based on a presentation given by Matthew D. Moles at “UK Society for Biomaterials Annual Conference 2013” held from 24 June 2013 to 25 June 2013 in Birmingham, United Kingdom.
• Contract Date: Aug 23, 2017