S.J. Venero-Fernandez
Risk factors for wheezing in infants born in Cuba
Venero-Fernandez, S.J.; Suarez-Medina, R.; Mora-Faife, E.C.; Garcia-Garcia, G.; Valle-Infante, I.; Gomez-Marrero, L.; Abreu-Suarez, G.; Gonzalez-Valdez, J.; Dania Fabro-Ortiz, D.; Fundora-Hernandez, H.; Venn, A.; Britton, J.; Fogarty, Andrew W.
Authors
R. Suarez-Medina
E.C. Mora-Faife
G. Garcia-Garcia
I. Valle-Infante
L. Gomez-Marrero
G. Abreu-Suarez
J. Gonzalez-Valdez
D. Dania Fabro-Ortiz
H. Fundora-Hernandez
A. Venn
J. Britton
Andrew W. Fogarty
Abstract
Background: Cuba is a unique country, and despite limited economic development, has an excellent health system. However, the prevalence of asthma symptoms in children in Havana, Cuba, is unusually high.
Aim: As early life exposures are critical to the aetiology of asthma, we have studied environmental influences on the risk of wheezing in Cuban infants.
Design: Cross-sectional study.
Methods: A random sample of 2032 children aged 12–15 months living in Havana was selected for inclusion in the cohort. Data were collected using questionnaires administered by researchers.
Results: Of 2032 infants invited to participate, 1956 (96%) infants provided data. The prevalence of any wheeze was 45%, severe wheeze requiring use of emergency services was 30% and recurrent wheeze on three or more occasions was 20%. The largest adjusted risk factors for any wheeze were presence of eczema [odds ratio (OR) 2.09; 95% confidence interval (CI) 1.48–2.94], family history of asthma (OR 2.05; 95% CI 1.60–2.62), poor ventilation in the house (OR 1.99; 95% CI 1.48–2.67), attendance at nursery (OR 1.78; 95% CI 1.24–2.57), male sex (OR1.52; 95% CI 1.19–1.96) and the number of smokers in the house (P < 0.03 for trend), OR 1.64 (95% CI 1.17–2.31) for three or more smokers in the house compared to no smokers in the household.
Conclusion: We have identified several risk factors for any wheeze in young infants living in modern day Cuba. As the prevalence of smoking in the house is high (51%), intervention studies are required to determine effective strategies to improve infant health.
Citation
Venero-Fernandez, S., Suarez-Medina, R., Mora-Faife, E., Garcia-Garcia, G., Valle-Infante, I., Gomez-Marrero, L., …Fogarty, A. W. (2013). Risk factors for wheezing in infants born in Cuba. QJM: An International Journal of Medicine, 106(11), https://doi.org/10.1093/qjmed/hct143
Journal Article Type | Article |
---|---|
Publication Date | Nov 11, 2013 |
Deposit Date | Apr 10, 2014 |
Publicly Available Date | Apr 10, 2014 |
Journal | QJM: An International Journal of Medicine |
Print ISSN | 1460-2725 |
Electronic ISSN | 1460-2393 |
Publisher | Oxford University Press |
Peer Reviewed | Peer Reviewed |
Volume | 106 |
Issue | 11 |
DOI | https://doi.org/10.1093/qjmed/hct143 |
Public URL | https://nottingham-repository.worktribe.com/output/719564 |
Publisher URL | http://qjmed.oxfordjournals.org/content/106/11/1023.full |
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Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0
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