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A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine

Barthelme, Alexandre; Richards, David; Mellor, Ian R.; Stockman, Robert A.

Authors

Alexandre Barthelme

David Richards

Ian R. Mellor

Robert A. Stockman



Abstract

Total syntheses of alkaloid cis-223B and xenovenine are reported in 3 and 4 steps respectively using a two-directional synthesis/triple reductive amination strategy, and their neurotoxic properties assessed.

Citation

Barthelme, A., Richards, D., Mellor, I. R., & Stockman, R. A. (2013). A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine. Chemical Communications, 49(89), https://doi.org/10.1039/c3cc46800c

Journal Article Type Article
Acceptance Date Sep 27, 2013
Online Publication Date Sep 27, 2013
Publication Date Nov 18, 2013
Deposit Date Jul 25, 2016
Publicly Available Date Jul 25, 2016
Journal Chemical Communications
Print ISSN 1359-7345
Electronic ISSN 1364-548X
Publisher Royal Society of Chemistry
Peer Reviewed Peer Reviewed
Volume 49
Issue 89
DOI https://doi.org/10.1039/c3cc46800c
Public URL http://eprints.nottingham.ac.uk/id/eprint/35316
Publisher URL http://pubs.rsc.org/en/Content/ArticleLanding/2013/CC/c3cc46800c#!divAbstract
Copyright Statement Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0

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ChemComm 2013.pdf (473 Kb)
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Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0





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