Vaccines against human enteric bacterial pathogens

Dougan, Gordon; Huett, Alan; Clare, Simon

Abstract

The development of vaccines against enteric bacterial pathogens presents a challenge because of the large number of pathogens capable of causing disease and the requirement to induce immunity that is effective in the gut. A new generation of enteric vaccines based either on live or non-living antigens delivered orally or by injection are reaching the clinic in the early phases of evaluation. However, considerable technical barriers have to be overcome before these vaccines reach the general population.

Citation

Dougan, G., Huett, A., & Clare, S. (2002). Vaccines against human enteric bacterial pathogens. British Medical Bulletin, 62(1), 113-123. https://doi.org/10.1093/bmb/62.1.113

• Journal Article Type: Review
• Publication Date: Aug 12, 2002
• Deposit Date: Aug 15, 2022
• Journal: British Medical Bulletin
• Print ISSN: 0007-1420
• Electronic ISSN: 1471-8391
• Publisher: Oxford University Press
• Peer Reviewed: Peer Reviewed
• Volume: 62
• Issue: 1
• Pages: 113-123
• DOI: https://doi.org/10.1093/bmb/62.1.113
• Keywords: antigens immunity vaccines pathogenic organism vaccine development
• Public URL: https://nottingham-repository.worktribe.com/output/5160642
• Publisher URL: https://academic.oup.com/bmb/article/62/1/113/281094?login=false