Lisa Vork
Patient-Specific Stress–Abdominal Pain Interaction in Irritable Bowel Syndrome: An Exploratory Experience Sampling Method Study
Vork, Lisa; Keszthelyi, Daniel; van Kuijk, Sander M.J.; Quetglas, Emilio G.; T�rnblom, Hans; Simr�n, Magnus; Aziz, Qasim; Corsetti, Maura; Tack, Jan; Mujagic, Zlatan; Leue, Carsten; Kruimel, Joanna W.; Masclee, Ad A.M.
Authors
Daniel Keszthelyi
Sander M.J. van Kuijk
Emilio G. Quetglas
Hans T�rnblom
Magnus Simr�n
Qasim Aziz
MAURA CORSETTI Maura.Corsetti@nottingham.ac.uk
Clinical Associate Professor
Jan Tack
Zlatan Mujagic
Carsten Leue
Joanna W. Kruimel
Ad A.M. Masclee
Abstract
INTRODUCTION:
Gastrointestinal symptoms in irritable bowel syndrome (IBS) have been correlated with psychological factors using retrospective symptom assessment. However, real-time symptom assessment might reveal the interplay between abdominal and affective symptoms more reliably in a longitudinal perspective. The aim was to evaluate the association between stress and abdominal pain, using the Experience Sampling Method (ESM) as a real-time, repeated measurement method.
METHODS:
Thirty-seven patients with IBS (26 women; mean age 36.7 years) and 36 healthy controls (HC; 24 women; mean age 31.1 years) completed an electronic ESM during 7 consecutive days. Abdominal pain and stress were scored on an 11-point Numeric Rating Scale at a maximum of 10 random moments each day.
RESULTS:
Abdominal pain scores were 2.21 points higher in patients with IBS compared with those in HC (P < 0.001), whereas stress levels did not differ significantly (B: 0.250, P = 0.406). In IBS, a 1-point increase in stress was associated with, on average, 0.10 points increase in abdominal pain (P = 0.017). In HC, this was only 0.02 (P = 0.002). Stress levels at t = ?1 were not a significant predictor for abdominal pain at t = 0 in both groups, and vice versa.
DISCUSSION:
Our results demonstrate a positive association between real-time stress and abdominal pain scores and indicate a difference in response to stress and not a difference in experienced stress per se. Furthermore, an in-the-moment rather than a longitudinal association is suggested. This study underlines the importance of considering the individual flow of daily life and supports the use of real-time measurement when interpreting potential influencers of abdominal symptoms in IBS.
Journal Article Type | Article |
---|---|
Acceptance Date | Jun 18, 2020 |
Publication Date | Jul 1, 2020 |
Deposit Date | Aug 18, 2020 |
Publicly Available Date | Aug 20, 2020 |
Journal | Clinical and Translational Gastroenterology |
Publisher | Nature Publishing Group |
Peer Reviewed | Peer Reviewed |
Volume | 11 |
Issue | 7 |
Article Number | e00209 |
DOI | https://doi.org/10.14309/ctg.0000000000000209 |
Keywords | Gastroenterology |
Public URL | https://nottingham-repository.worktribe.com/output/4841600 |
Publisher URL | https://journals.lww.com/ctg/FullText/2020/07000/Patient_Specific_Stress_Abdominal_Pain_Interaction.12.aspx |
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Publisher Licence URL
https://creativecommons.org/licenses/by-nc-nd/4.0/
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