Editorial Nonsteroidal Anti-inflammatory Drugs in the Perioperative Period: Current Controversies and Concerns

Joshi, Girish P; Kehlet, Henrik; Lobo, Dileep N

Abstract

Non-steroidal anti-inflammatory drugs (NSAID) and cyclo-oxygenase (COX)-2 specific inhibitors provide significant analgesic and opioid-sparing benefits. However, these analgesics are commonly avoided due to concerns of potential adverse effects. The evidence for NSAID-related adverse effects is conflicting and of poor quality, and these analgesics are safer than what has been implied. Thus, it is imperative that NSAIDs or COX-2 specific inhibitors are administered routinely unless there are contraindications.

Citation

Joshi, G. P., Kehlet, H., & Lobo, D. N. (in press). Editorial Nonsteroidal Anti-inflammatory Drugs in the Perioperative Period: Current Controversies and Concerns. British Journal of Anaesthesia,

• Journal Article Type: Editorial
• Acceptance Date: Oct 30, 2024
• Deposit Date: Oct 30, 2024
• Journal: British Journal of Anaesthesia
• Print ISSN: 0007-0912
• Electronic ISSN: 1471-6771
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Keywords: perioperative pain; analgesics; nonsteroidal anti-inflammatory drugs; acute kidney injury; persistent postoperative opioid use
• Public URL: https://nottingham-repository.worktribe.com/output/41141582