L. J. Bridge
Distinguishing possible mechanisms for auxin-mediated developmental control in Arabidopsis: Models with two Aux/IAA and ARF proteins, and two target gene-sets
Bridge, L. J.; Mirams, G. R.; Kieffer, M. L.; King, J. R.; Kepinski, S.
Authors
Prof. GARY MIRAMS GARY.MIRAMS@NOTTINGHAM.AC.UK
Professor of Mathematical Biology
M. L. Kieffer
J. R. King
S. Kepinski
Abstract
New models of gene transcriptional responses to auxin signalling in Arabidopsis are presented. This work extends a previous model of auxin signalling to include networks of gene-sets which may control developmental responses along auxin gradients. Key elements of this new study include models of signalling pathways and networks involving two Aux-IAA proteins (IAAs), auxin response factors (ARFs) and gene targets. Hypotheses for the gene network topologies which may be involved in developmental responses have been tested against experimental observations for root hair growth in particular. In studying these models, we provide a framework for the analysis of auxin signalling with multiple IAAs and ARFs, and discuss the implications of bistability in such systems. © 2011 Elsevier Inc..
Citation
Bridge, L. J., Mirams, G. R., Kieffer, M. L., King, J. R., & Kepinski, S. (2012). Distinguishing possible mechanisms for auxin-mediated developmental control in Arabidopsis: Models with two Aux/IAA and ARF proteins, and two target gene-sets. Mathematical Biosciences, 235(1), 32-44. https://doi.org/10.1016/j.mbs.2011.10.005
Journal Article Type | Article |
---|---|
Acceptance Date | Oct 21, 2011 |
Online Publication Date | Oct 31, 2011 |
Publication Date | Jan 1, 2012 |
Deposit Date | Jan 14, 2020 |
Journal | Mathematical Biosciences |
Print ISSN | 0025-5564 |
Electronic ISSN | 1879-3134 |
Publisher | Elsevier |
Peer Reviewed | Peer Reviewed |
Volume | 235 |
Issue | 1 |
Pages | 32-44 |
DOI | https://doi.org/10.1016/j.mbs.2011.10.005 |
Public URL | https://nottingham-repository.worktribe.com/output/3217613 |
Publisher URL | https://www.sciencedirect.com/science/article/pii/S0025556411001519 |
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