Impact of the COVID-19 pandemic on hospital episodes for falls and fractures associated with new-onset disability and frailty in England: a national cohort study

Thomas, Seth; Littleboy, Kathryn; Foubert, Josephine; Nafilyan, Vahe; Bannister, Neil; Routen, Ash; Morriss, Richard; Khunti, Kamlesh; Armstrong, Natalie; Gray, Laura J; Gordon, Adam L

Abstract

Background: Older people with frailty are at risk of harm from immobility or isolation, yet data about how COVID-19 lockdowns affected them are limited. Falls and fractures are easily measurable adverse outcomes correlated with frailty. We investigated whether English hospital admission rates for falls and fractures varied from the expected trajectory during the COVID-19 pandemic, and how these varied by frailty status. Methods: NHS England Hospital Episode Statistics Admitted Patient Care data were analysed for observed versus predicted outcome rates for 24 January 2020 to 31 December 2021. An auto-regressive integrated moving average time-series model was trained using falls and fracture incidence data from 2013 to 2018 and validated using data from 2019. Models included national and age-, sex- and region-stratified forecasts. Outcome measures were hospital admissions for falls, fractures, and falls and fractures combined. Frailty was defined using the Hospital Frailty Risk Score. Results: 144,148,915 pre-pandemic hospital admissions were compared with 42,267,318 admissions after pandemic onset. For the whole population, falls and fracture rates were below predicted for the first period of national lockdown, followed by a rapid return to rates close to predicted. Thereafter, rates followed expected trends. For people living with frailty, however, falls and fractures increased above expected rates during periods of national lockdown and remained elevated throughout the study period. Effects of frailty were independent of age. Conclusions: People living with frailty experienced increased fall and fracture rates above expected during and following periods of national lockdown. These remained persistently elevated throughout the study period.

Citation

Thomas, S., Littleboy, K., Foubert, J., Nafilyan, V., Bannister, N., Routen, A., Morriss, R., Khunti, K., Armstrong, N., Gray, L. J., & Gordon, A. L. (2024). Impact of the COVID-19 pandemic on hospital episodes for falls and fractures associated with new-onset disability and frailty in England: a national cohort study. Age and Ageing, 53(4), Article afae071. https://doi.org/10.1093/ageing/afae071

• Journal Article Type: Article
• Acceptance Date: Feb 26, 2024
• Online Publication Date: Apr 6, 2024
• Publication Date: 2024-04
• Deposit Date: Feb 28, 2024
• Publicly Available Date: Apr 7, 2025
• Journal: Age and Ageing
• Print ISSN: 0002-0729
• Electronic ISSN: 1468-2834
• Publisher: Oxford University Press
• Peer Reviewed: Peer Reviewed
• Volume: 53
• Issue: 4
• Article Number: afae071
• DOI: https://doi.org/10.1093/ageing/afae071
• Keywords: Fractures, Bone - diagnosis - epidemiology, Pandemics, fractures, frailty, Frail Elderly, Communicable Disease Control, COVID-19, older people, Aged, Humans, Frailty - diagnosis - epidemiology, COVID-19 - epidemiology, falls, Hospitals, Cohort Studies
• Public URL: https://nottingham-repository.worktribe.com/output/31889608
• Publisher URL: https://academic.oup.com/ageing/article/53/4/afae071/7641740