Methylprednisolone, intravenous immunoglobulin, tocilizimab or anakinra for children with Paediatric Inflammatory Multisystem Syndrome temporally associated with SARS CoV-2 (PIMS-TS, MIS-C) – report from a randomised, controlled, open-label, platform trial

Faust, Saul N.; Jones, Christine E.; Staplin, Natalie; Whittaker, Elizabeth; Jaki, Thomas; Juszczak, Ed; Spata, Enti; Wan, Mandy; Bamford, Alasdair; Dmitri, Paul; Finn, Adam; Furness, John; Ramanan, Athimalaipet V.; Gale, Chris; Cathie, Katrina; Drysdale, Simon; Bernatoniene, Jolanta; Murray, Clare; Roehr, Charles C.; Fleming, Paul F.; Riordan, Andrew; Bandi, Srini; Jyothish, Deepthi; Evans, Jennifer; Emonts, Marieke; Kelly, Dominic; Pathan, Nazima; Davies, Patrick; Hague, Rosie; Pollock, Louisa; Sample, Malcolm G.; Peto, Leon; Kenneth Baillie, J; Buch, Maya; Jeffery, Katie; Knight, Marian; Shen Lim, Wei; Montgomery, Alan; Mukherjee, Aparna; Mumford, Andrew; Rowan, Kathryn; Thwaites, Guy; Mafham, Marion; Emberson, Jonathan; Landray, Martin J; Horby, Peter W; Haynes, Richard; RECOVERY Collaborative Group, RECOVERY Collaborative Group

Methylprednisolone, intravenous immunoglobulin, tocilizimab or anakinra for children with Paediatric Inflammatory Multisystem Syndrome temporally associated with SARS CoV-2 (PIMS-TS, MIS-C) – report from a randomised, controlled, open-label, platform trial

Faust, Saul N.; Jones, Christine E.; Staplin, Natalie; Whittaker, Elizabeth; Jaki, Thomas; Juszczak, Ed; Spata, Enti; Wan, Mandy; Bamford, Alasdair; Dmitri, Paul; Finn, Adam; Furness, John; Ramanan, Athimalaipet V.; Gale, Chris; Cathie, Katrina; Drysdale, Simon; Bernatoniene, Jolanta; Murray, Clare; Roehr, Charles C.; Fleming, Paul F.; Riordan, Andrew; Bandi, Srini; Jyothish, Deepthi; Evans, Jennifer; Emonts, Marieke; Kelly, Dominic; Pathan, Nazima; Davies, Patrick; Hague, Rosie; Pollock, Louisa; Sample, Malcolm G.; Peto, Leon; Kenneth Baillie, J; Buch, Maya; Jeffery, Katie; Knight, Marian; Shen Lim, Wei; Montgomery, Alan; Mukherjee, Aparna; Mumford, Andrew; Rowan, Kathryn; Thwaites, Guy; Mafham, Marion; Emberson, Jonathan; Landray, Martin J; Horby, Peter W; Haynes, Richard; RECOVERY Collaborative Group, RECOVERY Collaborative Group

Authors

Saul N. Faust

Christine E. Jones

Natalie Staplin

Elizabeth Whittaker

Thomas Jaki

Professor ED JUSZCZAK ED.JUSZCZAK@NOTTINGHAM.AC.UK
Professor of Clinical Trials and Statistics in Medicine

Enti Spata

Mandy Wan

Alasdair Bamford

Paul Dmitri

Adam Finn

John Furness

Athimalaipet V. Ramanan

Chris Gale

Katrina Cathie

Simon Drysdale

Jolanta Bernatoniene

Clare Murray

Charles C. Roehr

Paul F. Fleming

Andrew Riordan

Srini Bandi

Deepthi Jyothish

Jennifer Evans

Marieke Emonts

Dominic Kelly

Nazima Pathan

Patrick Davies

Rosie Hague

Louisa Pollock

Malcolm G. Sample

Leon Peto

J Kenneth Baillie

Maya Buch

Katie Jeffery

Marian Knight

Wei Shen Lim

ALAN MONTGOMERY ALAN.MONTGOMERY@NOTTINGHAM.AC.UK
Director Nottingham Clinical Trials Unit

Aparna Mukherjee

Andrew Mumford

Kathryn Rowan

Guy Thwaites

Marion Mafham

Jonathan Emberson

Martin J Landray

Peter W Horby

Richard Haynes

RECOVERY Collaborative Group RECOVERY Collaborative Group

Journal Article Type	Article
Acceptance Date	Nov 17, 2023
Deposit Date	Nov 22, 2023
Journal	The Lancet Child & Adolescent Health
Electronic ISSN	2352-4642
Publisher	Elsevier
Peer Reviewed	Peer Reviewed
Public URL	https://nottingham-repository.worktribe.com/output/27592432
Additional Information	Writing committee of the RECOVERY Collaborative Group.

This file is under embargo due to copyright reasons.

Developing guidance for a risk-proportionate approach to blinding statisticians within clinical trials: a mixed methods study (2023)
Journal Article

A systematic review of randomisation method use in RCTs and association of trial design characteristics with method selection (2022)
Journal Article

Dietary nitrate supplementation for preventing and reducing the severity of winter infections, including COVID-19, in care homes (BEET-Winter)-a randomised placebo-controlled feasibility trial (2022)
Journal Article

Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis (2022)
Journal Article

Blinding of study statisticians in clinical trials: a qualitative study in UK clinical trials units (2022)
Journal Article

Methylprednisolone, intravenous immunoglobulin, tocilizimab or anakinra for children with Paediatric Inflammatory Multisystem Syndrome temporally associated with SARS CoV-2 (PIMS-TS, MIS-C) – report from a randomised, controlled, open-label, platform trial

Authors

You might also like

Downloadable Citations