Ayesha Sulthana
Gut microbiome-based dietary intervention in Parkinson disease subject: A case report
Sulthana, Ayesha; Paneyala, Shasthara; Narayan, Meghana Kowlagi; Ahmed Hediyal, Tousif; Sharma, Sonali; Senthilkumar, Arunsaikiran; Dave, Paul; Mahalakshmi, Arehally M; Chidambaram, Saravana Babu; Monaghan, Tanya M; Sulakhe, Dinanath
Authors
Shasthara Paneyala
Meghana Kowlagi Narayan
Tousif Ahmed Hediyal
Sonali Sharma
Arunsaikiran Senthilkumar
Paul Dave
Arehally M Mahalakshmi
Saravana Babu Chidambaram
TANYA MONAGHAN Tanya.Monaghan@nottingham.ac.uk
Clinical Associate Professor in Luminal Gastroenterology
Dinanath Sulakhe
Abstract
A 54-year-old woman was seeking medical treatment for Parkinson disease (PD) in the neurology outpatient department in JSS Hospital, Mysore, India. She was challenged in terms of reduced mobility and had sought several treatment options to control her PD symptoms without successful outcome. After examination and confirmation of diagnosis, the decision was taken to design a precision nutritional intervention using a gut microbiome-based diet combined with medical treatment. After 2 months of a superfood dietary intervention, the patient showed signs of clinical improvement as evidenced by improved mobility and a change in the Hoehn and Yahr clinical severity scale from stages 3 to 2. In conclusion, it is possible to modulate the gut microbiome to reverse the established gut dysbiosis associated with the neurodegenerative process in PD, which can lead to clinical benefit by reducing functional disability.
Citation
Sulthana, A., Paneyala, S., Narayan, M. K., Ahmed Hediyal, T., Sharma, S., Senthilkumar, A., …Sulakhe, D. (2023). Gut microbiome-based dietary intervention in Parkinson disease subject: A case report. International Journal of Nutrition, Pharmacology, Neurological Diseases, 13(3), 158-165. https://doi.org/10.4103/ijnpnd.ijnpnd_8_23
Journal Article Type | Article |
---|---|
Acceptance Date | Mar 20, 2023 |
Online Publication Date | Jul 27, 2023 |
Publication Date | 2023-07 |
Deposit Date | Jul 31, 2023 |
Publicly Available Date | Aug 16, 2023 |
Journal | International Journal of Nutrition, Pharmacology, Neurological Diseases |
Print ISSN | 2231-0738 |
Publisher | Medknow Publications |
Peer Reviewed | Peer Reviewed |
Volume | 13 |
Issue | 3 |
Pages | 158-165 |
DOI | https://doi.org/10.4103/ijnpnd.ijnpnd_8_23 |
Keywords | Gut microbiome; Parkinson disease; Gut dysbiosis; Nutrition; Precision diet |
Public URL | https://nottingham-repository.worktribe.com/output/23632594 |
Publisher URL | https://journals.lww.com/ijnp/Fulltext/2023/13030/Gut_microbiome_based_dietary_intervention_in.5.aspx |
Files
Gut Microbiome Based Dietary Intervention In.5
(3.3 Mb)
PDF
Publisher Licence URL
https://creativecommons.org/licenses/by-nc-sa/4.0/
You might also like
Clostridium difficile infection: epidemiology, diagnosis and understanding transmission
(2016)
Journal Article
Potential of lactoferrin to prevent antibiotic-induced Clostridium difficile infection
(2016)
Journal Article
New perspectives in Clostridium difficile disease pathogenesis
(2015)
Journal Article
Downloadable Citations
About Repository@Nottingham
Administrator e-mail: discovery-access-systems@nottingham.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search