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Treatment interventions for hand fractures and joint injuries: a scoping review of randomized controlled trials

Mousoulis, Christos; Thomas, Kim; Leighton, Paul; Deshmukh, Sandeep; Grindlay, Douglas; Karantana, Alexia


Christos Mousoulis

Associate Professor of Applied Health Services Research

Sandeep Deshmukh

Douglas Grindlay

Clinical Associate Professor in Hand Surgery


The aim of this study was to identify and assess all existing randomized studies on treatment interventions for hand fractures and joint injuries, to inform practice and plan future research. PubMed, Cochrane CENTRAL, MEDLINE and Embase were searched. We identified 78 randomized controlled trials published over 35 years, covering seven anatomical areas of the hand. We report on sources of bias, sample size, follow-up length and retention, outcome measures and reporting. In terms of interventions studied, the trials were extremely heterogeneous, so it is difficult to draw conclusions on individual treatments. The published randomized controlled clinical trial (RCT) evidence for hand fractures and joint injuries is narrow in scope and of generally low methodological quality. Mapping provides a useful resource and stepping stone for planning further research. There is a need for high-quality, collaborative research to guide management of a much wider breadth of common hand injuries.


Mousoulis, C., Thomas, K., Leighton, P., Deshmukh, S., Grindlay, D., & Karantana, A. (2020). Treatment interventions for hand fractures and joint injuries: a scoping review of randomized controlled trials. Journal of Hand Surgery (European Volume), 45(2), 111-118.

Journal Article Type Article
Acceptance Date Jun 27, 2019
Online Publication Date Aug 5, 2019
Publication Date 2020-02
Deposit Date Jul 24, 2019
Publicly Available Date Jul 24, 2019
Print ISSN 1753-1934
Electronic ISSN 2043-6289
Publisher SAGE Publications
Peer Reviewed Peer Reviewed
Volume 45
Issue 2
Pages 111-118
Public URL
Publisher URL


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