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A beginner's guide to systems simulation in immunology

Figueredo, Grazziela P.; Siebers, Peer-Olaf; Aickelin, Uwe; Foan, Stephanie

Authors

Uwe Aickelin uwe.aickelin@nottingham.ac.uk

Stephanie Foan



Contributors

Carlos A. Coello Coello
Editor

Natalio Krasnogor
Editor

P. Liò
Editor

G. Nicosia
Editor

M. Pavone
Editor

Abstract

Some common systems modelling and simulation approaches for immune problems are Monte Carlo simulations, system dynamics, discrete-event simulation and agent-based simulation. These methods, however, are still not widely adopted in immunology research. In addition, to our knowledge, there is few research on the processes for the development of simulation models for the immune system. Hence, for this work, we have two contributions to knowledge. The first one is to show the importance of
systems simulation to help immunological research and to draw the attention of simulation developers to this research field. The second contribution is the introduction of a quick guide containing the main steps for modelling and simulation in immunology, together with challenges that occur during the model development. Further, this paper introduces an example of a simulation problem, where we test our guidelines.

Citation

Figueredo, G. P., Siebers, P., Aickelin, U., & Foan, S. (2012). A beginner's guide to systems simulation in immunology. In J. Greensmith, C. A. Coello Coello, N. Krasnogor, P. LiĆ², G. Nicosia, & M. Pavone (Eds.), Artificial immune systems: 11th International Conference, ICARIS 2012, Taormina, Italy, August 28-31, 2012: proceedingsSpringer

Publication Date Jan 1, 2012
Deposit Date Jun 19, 2013
Publicly Available Date Jun 19, 2013
Peer Reviewed Peer Reviewed
Issue 7597
Series Title Lecture notes in computer science
Book Title Artificial immune systems: 11th International Conference, ICARIS 2012, Taormina, Italy, August 28-31, 2012: proceedings
ISBN 9783642337574
Public URL http://eprints.nottingham.ac.uk/id/eprint/2032
Publisher URL http://www.springer.com/computer/theoretical+computer+science/book/978-3-642-33756-7
Copyright Statement Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf
Additional Information Paper presented at: 11th International Conference on Artificial Immune Systems, ICARIS 2012, Taormina, Italy, 28-31 August 2012.

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf





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