Outputs (3)

Assessing muscle protein synthesis rates in vivo in humans: the deuterated water (2H2O) method (2024)
Journal Article
Holwerda, A. M., Atherton, P. J., Smith, K., Wilkinson, D. J., Phillips, S. M., & van Loon, L. J. (2024). Assessing muscle protein synthesis rates in vivo in humans: the deuterated water (2H2O) method. Journal of Nutrition, 154(11), 3177-3189. https://doi.org/10.1016/j.tjnut.2024.09.012

Skeletal muscle tissue is in a constant state of turnover, with muscle tissue protein synthesis and breakdown rates ranging between 1-2 % across the day in vivo in humans. Muscle tissue remodeling is largely controlled by the up- and down-regulation... Read More about Assessing muscle protein synthesis rates in vivo in humans: the deuterated water (2H2O) method.

Bed‐rest and exercise remobilization: Concurrent adaptations in muscle glucose and protein metabolism (2024)
Journal Article
Shur, N. F., Simpson, E. J., Crossland, H., Constantin, D., Cordon, S. M., Constantin-Teodosiu, D., Stephens, F. B., Brook, M. S., Atherton, P. J., Smith, K., Wilkinson, D. J., Mougin, O. E., Bradley, C., Macdonald, I. A., & Greenhaff, P. L. (2024). Bed‐rest and exercise remobilization: Concurrent adaptations in muscle glucose and protein metabolism. Journal of Cachexia, Sarcopenia and Muscle, 15(2), 603-614. https://doi.org/10.1002/jcsm.13431

Background
Bed-rest (BR) of only a few days duration reduces muscle protein synthesis and induces skeletal muscle atrophy and insulin resistance, but the scale and juxtaposition of these events have not been investigated concurrently in the same ind... Read More about Bed‐rest and exercise remobilization: Concurrent adaptations in muscle glucose and protein metabolism.

Protein dose requirements to maximise skeletal muscle protein synthesis after repeated bouts of resistance exercise in young trained women (2023)
Journal Article
Mallinson, J. E., Wardle, S. L., O'Leary, T. J., Greeves, J. P., Cegielski, J., Bass, J., Brook, M. S., Wilkinson, D. J., Smith, K., Atherton, P. J., & Greenhaff, P. L. (2023). Protein dose requirements to maximise skeletal muscle protein synthesis after repeated bouts of resistance exercise in young trained women. Scandinavian Journal of Medicine and Science in Sports, 33(12), 2470-2481. https://doi.org/10.1111/sms.14506

Studies examining the effect of protein (PRO) feeding on post resistance exercise (RE) muscle protein synthesis (MPS) have primarily been performed in men, and little evidence is available regarding the quantity of PRO required to maximally stimulate... Read More about Protein dose requirements to maximise skeletal muscle protein synthesis after repeated bouts of resistance exercise in young trained women.