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Outputs (633)

Elective peri-operative management of adults taking glucagon-like peptide-1 receptor agonists, glucose-dependent insulinotropic peptide agonists andsodium-glucose cotransporter-2 inhibitors: a multidisciplinary consensus statement: A consensus statement from the Association of Anaesthetists, Association of BritishClinical Diabetologists, British Obesity and Metabolic Surgery Society, Centrefor Perioperative Care, Joint British Diabetes Societies for Inpatient Care, RoyalCollege of Anaesthetists, Society for Obesity and Bariatric Anaesthesia and UK Clinical Pharmacy Association (2025)
Journal Article
El-Boghdadly, K., Dhesi, J., Fabb, P., Levy, N., Lobo, D. N., McKechnie, A., Mustafa, O., Newland-Jones, P., Patel, A., Pournaras, D. J., Clare, K., & Dhatariya, K. (2025). Elective peri-operative management of adults taking glucagon-like peptide-1 receptor agonists, glucose-dependent insulinotropic peptide agonists andsodium-glucose cotransporter-2 inhibitors: a multidisciplinary consensus statement: A consensus statement from the Association of Anaesthetists, Association of BritishClinical Diabetologists, British Obesity and Metabolic Surgery Society, Centrefor Perioperative Care, Joint British Diabetes Societies for Inpatient Care, RoyalCollege of Anaesthetists, Society for Obesity and Bariatric Anaesthesia and UK Clinical Pharmacy Association. Anaesthesia, https://doi.org/10.1111/anae.16541

Introduction: Glucagon-like peptide-1 receptor agonists, dual glucose-dependent insulinotropic peptide receptor agonists and sodium-glucose cotransporter-2 inhibitors are used increasingly in patients receiving peri-operative care. These drugs may be... Read More about Elective peri-operative management of adults taking glucagon-like peptide-1 receptor agonists, glucose-dependent insulinotropic peptide agonists andsodium-glucose cotransporter-2 inhibitors: a multidisciplinary consensus statement: A consensus statement from the Association of Anaesthetists, Association of BritishClinical Diabetologists, British Obesity and Metabolic Surgery Society, Centrefor Perioperative Care, Joint British Diabetes Societies for Inpatient Care, RoyalCollege of Anaesthetists, Society for Obesity and Bariatric Anaesthesia and UK Clinical Pharmacy Association.

Deconditioning in quiescent Crohn’s Disease patients with heightened fatigue perception (2025)
Journal Article
McGing, J. J., Serres, S., Nicholas, R., Gupta, A., Radford, S. J., Nixon, A. V., Mallinson, J., Bradley, C., Bawden, S., Francis, S. T., Greenhaff, P. L., & Moran, G. W. (2025). Deconditioning in quiescent Crohn’s Disease patients with heightened fatigue perception. Journal of Crohn's and Colitis, 19(1), Article jjae194. https://doi.org/10.1093/ecco-jcc/

Background & Objective

IBD fatigue aetiology is poorly understood. This study quantified body composition and physical function alongside proton magnetic resonance imaging (1H MRI) and spectroscopy (31P MRS) measures of organ structure and functio... Read More about Deconditioning in quiescent Crohn’s Disease patients with heightened fatigue perception.

Low-temperature vacuum evaporation as a novel dehydration process for the long-term preservation of transplantable human corneal tissue (2025)
Journal Article
McIntosh, O. D., Britchford, E. R., Beeken, L. J., Hopkinson, A., & Sidney, L. E. (2025). Low-temperature vacuum evaporation as a novel dehydration process for the long-term preservation of transplantable human corneal tissue. Cell and Tissue Banking, 26(1), Article 7. https://doi.org/10.1007/s10561-024-10155-y

Globally there is a shortage of available donor corneas with only 1 cornea available for every 70 needed. A large limitation to corneal transplant surgery is access to quality donor tissue due to inadequate eye donation services and infrastructure in... Read More about Low-temperature vacuum evaporation as a novel dehydration process for the long-term preservation of transplantable human corneal tissue.

Five year mortality in an RCT of a lung cancer biomarker to select people for low dose CT screening (2025)
Journal Article
Sullivan, F. M., Mair, F. S., Anderson, W., Chew, C., Dorward, A., Haughney, J., Hogarth, F., Kendrick, D., Littleford, R., McConnachie, A., McCowan, C., McMeekin, N., Patel, M., Rauchhaus, P., Daly, F., Ritchie, L., Robertson, J., Sarvesvaran, J., Sewell, H., Taylor, T., …Schembri, S. (2025). Five year mortality in an RCT of a lung cancer biomarker to select people for low dose CT screening. PLoS ONE, 20(1), Article e0306163. https://doi.org/10.1371/journal.pone.0306163

The role of biomarkers in risk-based early detection of lung cancer may enable screening to become cost effective and widely accessible. EarlyCDT-Lung is an example of such a blood-based autoantibody biomarker which may improve accessibility to Low d... Read More about Five year mortality in an RCT of a lung cancer biomarker to select people for low dose CT screening.

COLOFIT: Development and Internal-External Validation of Models Using Age, Sex, Faecal Immunochemical and Blood Tests to Optimise Diagnosis of Colorectal Cancer in Symptomatic Patients (2025)
Journal Article
Crooks, C. J., West, J., Jones, J., Hamilton, W., Bailey, S. E., Abel, G., Banerjea, A., Rees, C. J., Tamm, A., Nicholson, B. D., Benton, S. C., Hunt, N., COLOFIT, R. G., & Humes, D. J. (2025). COLOFIT: Development and Internal-External Validation of Models Using Age, Sex, Faecal Immunochemical and Blood Tests to Optimise Diagnosis of Colorectal Cancer in Symptomatic Patients. Alimentary Pharmacology and Therapeutics, 61(5), 852-864. https://doi.org/10.1111/apt.18459

Background: Colorectal cancer (CRC) is the third most common cancer in the United Kingdom and the second largest cause of cancer death. Aim: To develop and validate a model using available information at the time of faecal immunochemical testing (FIT... Read More about COLOFIT: Development and Internal-External Validation of Models Using Age, Sex, Faecal Immunochemical and Blood Tests to Optimise Diagnosis of Colorectal Cancer in Symptomatic Patients.

Effects of Ramadan intermittent fasting on hormones regulating appetite in healthy individuals: A systematic review and meta-analysis (2025)
Journal Article
Alogaiel, D. M., Alsuwaylihi, A., Alotaibi, M. S., Macdonald, I. A., & Lobo, D. N. (2025). Effects of Ramadan intermittent fasting on hormones regulating appetite in healthy individuals: A systematic review and meta-analysis. Clinical Nutrition, 45, 250-261. https://doi.org/10.1016/j.clnu.2025.01.005

Background and aims: This systematic review and meta-analysis aimed to examine the effect of Ramadan intermittent fasting on appetite-regulating hormones including leptin, ghrelin, insulin, gastrin, glucagon-like peptide-1, peptide YY, and cholecysto... Read More about Effects of Ramadan intermittent fasting on hormones regulating appetite in healthy individuals: A systematic review and meta-analysis.

European Guideline on Chronic Nausea and Vomiting—A UEG and ESNM Consensus for Clinical Management (2025)
Journal Article
Malagelada, C., Keller, J., Sifrim, D., Serra, J., Tack, J., Mulak, A., Stengel, A., Aguilar, A., Drewes, A. M., Josefsson, A., Bonaz, B., Dumitrascu, D., Keszthelyi, D., Barba, E., Carbone, F., Zerbib, F., Marchegiani, G., Hauser, G., Gourcerol, G., Tornblom, H., …Surdea-Blaga, T. (2025). European Guideline on Chronic Nausea and Vomiting—A UEG and ESNM Consensus for Clinical Management. United European Gastroenterology Journal, https://doi.org/10.1002/ueg2.12711

Introduction: Chronic nausea and vomiting are symptoms of a wide range of gastrointestinal and non-gastrointestinal conditions. Diagnosis can be challenging and requires a systematic and well-structured approach. If the initial investigation for stru... Read More about European Guideline on Chronic Nausea and Vomiting—A UEG and ESNM Consensus for Clinical Management.

Time Below Range and Its Influence on Hypoglycemia Awareness and Severe Hypoglycemia: Insights From the Association of British Clinical Diabetologists Study (2025)
Journal Article
Deshmukh, H., Wilmot, E. G., Choudhary, P., Ssemmondo, E., Barnes, D., Walker, N., Walton, C., Ryder, R. E., & Sathyapalan, T. (2025). Time Below Range and Its Influence on Hypoglycemia Awareness and Severe Hypoglycemia: Insights From the Association of British Clinical Diabetologists Study. Diabetes Care, Article dc241833. https://doi.org/10.2337/dc24-1833

OBJECTIVE
This study aimed to explore the relationship between time below range (TBR), impaired awareness of hypoglycemia (IAH), and severe hypoglycemia (SH).

RESEARCH DESIGN AND METHODS
This cross-sectional study analyzed data from individuals... Read More about Time Below Range and Its Influence on Hypoglycemia Awareness and Severe Hypoglycemia: Insights From the Association of British Clinical Diabetologists Study.