A novel liposomal S-propargyl-cysteine: a sustained release of hydrogen sulfide reducing myocardial fibrosis via TGF-β1/Smad pathway
(2019)
Journal Article
Hieu Tran, B., Yu, Y., Chang, L., Tan, B., Jia, W., Xiong, Y., …Zhun Zhu, Y. (2019). A novel liposomal S-propargyl-cysteine: a sustained release of hydrogen sulfide reducing myocardial fibrosis via TGF-β1/Smad pathway. International Journal of Nanomedicine, 2019:14, 10061-10077. https://doi.org/10.2147/IJN.S216667
Purpose: S-propargyl-cysteine (SPRC; alternatively known as ZYZ-802) is a novel modulator of endogenous tissue H2S concentrations with known cardioprotective and anti-inflammatory effects. However, its rapid metabolism and excretion have limited its... Read More about A novel liposomal S-propargyl-cysteine: a sustained release of hydrogen sulfide reducing myocardial fibrosis via TGF-β1/Smad pathway.