Outputs (2)

A novel liposomal S-propargyl-cysteine: a sustained release of hydrogen sulfide reducing myocardial fibrosis via TGF-β1/Smad pathway (2019)
Journal Article
Hieu Tran, B., Yu, Y., Chang, L., Tan, B., Jia, W., Xiong, Y., Dai, T., Zhong, R., Zhang, W., Minh Le, V., Rose, P., Wang, Z., Mao, Y., & Zhun Zhu, Y. (2019). A novel liposomal S-propargyl-cysteine: a sustained release of hydrogen sulfide reducing myocardial fibrosis via TGF-β1/Smad pathway. International Journal of Nanomedicine, 2019:14, 10061-10077. https://doi.org/10.2147/IJN.S216667

Purpose: S-propargyl-cysteine (SPRC; alternatively known as ZYZ-802) is a novel modulator of endogenous tissue H2S concentrations with known cardioprotective and anti-inflammatory effects. However, its rapid metabolism and excretion have limited its... Read More about A novel liposomal S-propargyl-cysteine: a sustained release of hydrogen sulfide reducing myocardial fibrosis via TGF-β1/Smad pathway.

An Appraisal of Developments in Allium Sulfur Chemistry: Expanding the Pharmacopeia of Garlic (2019)
Journal Article
Rose, P., Moore, P. K., Whiteman, M., & Zhu, Y.-Z. (2019). An Appraisal of Developments in Allium Sulfur Chemistry: Expanding the Pharmacopeia of Garlic. Molecules, 24(21), Article 4006. https://doi.org/10.3390/molecules24214006

Alliums and allied plant species are rich sources of sulfur compounds that have effects on vascular homeostasis and the control of metabolic systems linked to nutrient metabolism in mammals. In view of the multiple biological effects ascribed to thes... Read More about An Appraisal of Developments in Allium Sulfur Chemistry: Expanding the Pharmacopeia of Garlic.