Skip to main content

Research Repository

Advanced Search

Outputs (4)

Protective effects of Asian green vegetables against oxidant induced cytotoxicity (2005)
Journal Article
Rose, P., Ong, C. N., & Whiteman, M. (2005). Protective effects of Asian green vegetables against oxidant induced cytotoxicity. World Journal of Gastroenterology, 11(48), 7607-7614. https://doi.org/10.3748/wjg.v11.i48.7607

Aim: To evaluate the antioxidant and phase II detoxification enzyme inducing ability of green leaf vegetables consumed in Asia.

Methods: Th e antioxidant properties of six commonly consumed Asian vegetables were determined using the ABTS, DPPH, d... Read More about Protective effects of Asian green vegetables against oxidant induced cytotoxicity.

Hydrogen sulfide protects colon cancer cells from chemopreventative agent β-phenylethyl isothiocyanate induced apoptosis (2005)
Journal Article
Rose, P., Moore, P. K., Ming, S. H., Nam, O. C., Armstrong, J. S., & Whiteman, M. (2005). Hydrogen sulfide protects colon cancer cells from chemopreventative agent β-phenylethyl isothiocyanate induced apoptosis. World Journal of Gastroenterology, 11(26), 3990-3997. https://doi.org/10.3748/wjg.v11.i26.3990

AIM: Hydrogen sulfide (H2S) is a prominent gaseous constituent of the gastrointestinal (GI) tract with known cytotoxic properties. Endogenous concentrations of H2S are reported to range between 0.2-3.4 mmol/L in the GI tract of mice and humans. Consi... Read More about Hydrogen sulfide protects colon cancer cells from chemopreventative agent β-phenylethyl isothiocyanate induced apoptosis.

Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells (2005)
Journal Article
Rose, P., Huang, Q., Ong, C. N., & Whiteman, M. (2005). Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells. Toxicology and Applied Pharmacology, 209(2), 105-113. https://doi.org/10.1016/j.taap.2005.04.010

A high dietary intake of cruciferous vegetables has been associated with a reduction in numerous human pathologies particularly cancer. In the current study, we examined the inhibitory effects of broccoli (Brassica oleracea var. italica) and watercre... Read More about Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells.

Hypochlorous acid-mediated mitochondrial dysfunction and apoptosis in human hepatoma HepG2 and human fetal liver cells: Role of mitochondrial permeability transition (2005)
Journal Article
Whiteman, M., Rose, P., Jia, L. S., Nam, S. C., Gek, S. T., Halliwell, B., & Armstrong, J. S. (2005). Hypochlorous acid-mediated mitochondrial dysfunction and apoptosis in human hepatoma HepG2 and human fetal liver cells: Role of mitochondrial permeability transition. Free Radical Biology and Medicine, 38(12), 1571-1584. https://doi.org/10.1016/j.freeradbiomed.2005.02.030

Liver cirrhosis is often preceded by overt signs of hepatitis, including parenchymal cell inflammation and infiltration of polymorphonuclear (PMN) leukocytes. Activated PMNs release both reactive oxygen species and reactive halogen species, including... Read More about Hypochlorous acid-mediated mitochondrial dysfunction and apoptosis in human hepatoma HepG2 and human fetal liver cells: Role of mitochondrial permeability transition.