Outputs (35)

Cerebral blood flow and arterial transit time responses to exercise training in older adults (2024)
Journal Article
Feron, J., Rahman, F., Fosstveit, S. H., Joyce, K. E., Gilani, A., Lohne-Seiler, H., Berntsen, S., Mullinger, K. J., Segaert, K., & Lucas, S. J. E. (2024). Cerebral blood flow and arterial transit time responses to exercise training in older adults. NeuroImage, 303, Article 120919. https://doi.org/10.1016/j.neuroimage.2024.120919

Brain vascular health worsens with age, as is made evident by resting grey matter cerebral blood flow (CBFGM) reductions and lengthening arterial transit time (ATTGM). Exercise training can improve aspects of brain health in older adults, yet its eff... Read More about Cerebral blood flow and arterial transit time responses to exercise training in older adults.

Determinants of cerebral blood flow and arterial transit time in healthy older adults (2024)
Journal Article
Feron, J., Segaert, K., Rahman, F., Fosstveit, S. H., Joyce, K. E., Gilani, A., Lohne-Seiler, H., Berntsen, S., Mullinger, K. J., & Lucas, S. J. (2024). Determinants of cerebral blood flow and arterial transit time in healthy older adults. Aging, 16(18), 12473-12497. https://doi.org/10.18632/aging.206112

Cerebral blood flow (CBF) and arterial transit time (ATT), markers of brain vascular health, worsen with age. The primary aim of this cross-sectional study was to identify modifiable determinants of CBF and ATT in healthy older adults (n = 78, aged 6... Read More about Determinants of cerebral blood flow and arterial transit time in healthy older adults.

Neurovascular coupling methods in healthy individuals using transcranial doppler ultrasonography: A systematic review and consensus agreement (2024)
Journal Article
Ball, J. D., Hills, E., Altaf, A., Ramesh, P., Green, M., Surti, F. B., Minhas, J. S., Robinson, T. G., Bond, B., Lester, A., Hoiland, R., Klein, T., Liu, J., Nasr, N., Junejo, R. T., Müller, M., Lecchini-Visintini, A., Mitsis, G., Burma, J. S., Smirl, J. D., …Beishon, L. . C. (2024). Neurovascular coupling methods in healthy individuals using transcranial doppler ultrasonography: A systematic review and consensus agreement. Journal of Cerebral Blood Flow and Metabolism, 44(12), 1409-1429. https://doi.org/10.1177/0271678X241270452

Neurovascular coupling (NVC) is the perturbation of cerebral blood flow (CBF) to meet varying metabolic demands induced by various levels of neural activity. NVC may be assessed by Transcranial Doppler ultrasonography (TCD), using task activation pro... Read More about Neurovascular coupling methods in healthy individuals using transcranial doppler ultrasonography: A systematic review and consensus agreement.

Simultaneous whole-head electrophysiological recordings using EEG and OPM-MEG (2024)
Journal Article
Seedat, Z. A., Pier, K. S., Holmes, N., Rea, M., Al-Hilaly, L., Tierney, T. M., Embury, C. M., Pardington, R., Mullinger, K. J., Cross, J. H., Boto, E., & Brookes, M. J. (2024). Simultaneous whole-head electrophysiological recordings using EEG and OPM-MEG. Imaging Neuroscience, 2, 1-15. https://doi.org/10.1162/imag_a_00179

Electroencephalography (EEG) and magnetoencephalography (MEG) non-invasively measure human brain electrophysiology. They differ in nature; MEG offers better performance whilst EEG (a wearable platform) is more practical. They are also complementary,... Read More about Simultaneous whole-head electrophysiological recordings using EEG and OPM-MEG.

Post‐task responses following working memory and movement are driven by transient spectral bursts with similar characteristics (2024)
Journal Article
Coleman, S. C., Seedat, Z. A., Pakenham, D. O., Quinn, A. J., Brookes, M. J., Woolrich, M. W., & Mullinger, K. J. (2024). Post‐task responses following working memory and movement are driven by transient spectral bursts with similar characteristics. Human Brain Mapping, 45(7), Article e26700. https://doi.org/10.1002/hbm.26700

The post-movement beta rebound has been studied extensively using magnetoencephalography (MEG) and is reliably modulated by various task parameters as well as illness. Our recent study showed that rebounds, which we generalise as “post-task responses... Read More about Post‐task responses following working memory and movement are driven by transient spectral bursts with similar characteristics.

Measurement of Frontal Midline Theta Oscillations using OPM-MEG (2023)
Journal Article
Rhodes, N., Rea, M., Boto, E., Rier, L., Shah, V., Hill, R. M., Osborne, J., Doyle, C., Holmes, N., Coleman, S. C., Mullinger, K., Bowtell, R., & Brookes, M. J. (2023). Measurement of Frontal Midline Theta Oscillations using OPM-MEG. NeuroImage, 271, Article 120024. https://doi.org/10.1016/j.neuroimage.2023.120024

Optically pumped magnetometers (OPMs) are an emerging lightweight and compact sensor that can measure magnetic fields generated by the human brain. OPMs enable construction of wearable magnetoencephalography (MEG) systems, which offer advantages over... Read More about Measurement of Frontal Midline Theta Oscillations using OPM-MEG.

Beyond the Beta Rebound: Post-Task Responses in Oscillatory Activity follow Cessation of Working Memory Processes (2022)
Journal Article
Coleman, S. C., Seedat, Z. A., Whittaker, A. C., Lenartowicz, A., & Mullinger, K. J. (2023). Beyond the Beta Rebound: Post-Task Responses in Oscillatory Activity follow Cessation of Working Memory Processes. NeuroImage, 265, Article 119801. https://doi.org/10.1016/j.neuroimage.2022.119801

Post-task responses (PTRs) are transitionary responses occurring for several seconds between the end of a stimulus/task and a period of rest. The most well-studied of these are beta band (13 – 30 Hz) PTRs in motor networks following movement, often c... Read More about Beyond the Beta Rebound: Post-Task Responses in Oscillatory Activity follow Cessation of Working Memory Processes.

Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study (2022)
Journal Article
Seedat, Z. A., Rier, L., Gascoyne, L. E., Cook, H., Woolrich, M. W., Quinn, A. J., Roberts, T. P. L., Furlong, P. L., Armstrong, C., St. Pier, K., Mullinger, K. J., Marsh, E. D., Brookes, M. J., & Gaetz, W. (2022). Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study. Human Brain Mapping, https://doi.org/10.1002/hbm.26118

Epilepsy is a highly heterogeneous neurological disorder with variable etiology, manifestation, and response to treatment. It is imperative that new models of epileptiform brain activity account for this variability, to identify individual needs and... Read More about Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study.

Across the adult lifespan the ipsilateral sensorimotor cortex negative BOLD response exhibits decreases in magnitude and spatial extent suggesting declining inhibitory control (2022)
Journal Article
Mayhew, S. D., Coleman, S. C., & Mullinger, K. J. (2022). Across the adult lifespan the ipsilateral sensorimotor cortex negative BOLD response exhibits decreases in magnitude and spatial extent suggesting declining inhibitory control. NeuroImage, 253, Article 119081. https://doi.org/10.1016/j.neuroimage.2022.119081

Ipsilateral sensorimotor (iSM1) cortex negative BOLD responses (NBR) are observed to unilateral tasks and are thought to reflect a functionally relevant component of sensorimotor inhibition. Evidence suggests that sensorimotor inhibitory mechanisms d... Read More about Across the adult lifespan the ipsilateral sensorimotor cortex negative BOLD response exhibits decreases in magnitude and spatial extent suggesting declining inhibitory control.

Measuring resting cerebral haemodynamics using MRI arterial spin labelling and transcranial Doppler ultrasound: comparison in younger and older adults (2021)
Journal Article
Burley, C. V., Francis, S. T., Whittaker, A. C., Mullinger, K. J., & Lucas, S. J. E. (2021). Measuring resting cerebral haemodynamics using MRI arterial spin labelling and transcranial Doppler ultrasound: comparison in younger and older adults. Brain and Behavior, 11(7), Article e02126. https://doi.org/10.1002/brb3.2126

Introduction: Resting cerebral blood flow (CBF) and perfusion measures have been used to determine brain health. Studies showing variation in resting CBF with age and fitness level using different imaging approaches have produced mixed findings. We a... Read More about Measuring resting cerebral haemodynamics using MRI arterial spin labelling and transcranial Doppler ultrasound: comparison in younger and older adults.