Outputs (4)

A mechanoresponsive nano-sized carrier achieves intracellular release of drug on external ultrasound stimulus (2022)
Journal Article
Catania, R., Onion, D., Russo, E., Zelzer, M., Mantovani, G., Huett, A., & Stolnik, S. (2022). A mechanoresponsive nano-sized carrier achieves intracellular release of drug on external ultrasound stimulus. RSC Advances, 12(26), 16561-16569. https://doi.org/10.1039/d2ra02307e

Control over intracellular release of therapeutic compounds incorporated into nano-carriers will open new possibilities for targeted treatments of various diseases including cancer, and viral and bacterial infections. Here we report our study on mech... Read More about A mechanoresponsive nano-sized carrier achieves intracellular release of drug on external ultrasound stimulus.

Development of a nanocapsule-loaded hydrogel for drug delivery for intraperitoneal administration (2022)
Journal Article
Teja Surikutchi, B., Obenza-Otero, R., Russo, E., Zelzer, M., Golán Cancela, I., Costoya, J. A., Crecente Campo, J., José Alonso, M., & Marlow, M. (2022). Development of a nanocapsule-loaded hydrogel for drug delivery for intraperitoneal administration. International Journal of Pharmaceutics, 622, Article 121828. https://doi.org/10.1016/j.ijpharm.2022.121828

Intraperitoneal (IP) drug delivery of chemotherapeutic agents, administered through hyperthermal intraperitoneal chemotherapy (HIPEC) and pressurized intraperitoneal aerosolized chemotherapy (PIPAC), is effective for the treatment of peritoneal malig... Read More about Development of a nanocapsule-loaded hydrogel for drug delivery for intraperitoneal administration.

Cell-controlled dynamic surfaces for skeletal stem cell growth and differentiation (2022)
Journal Article
Anderson, H. J., Sahoo, J. K., Wells, J., van Nuffel, S., Dhowre, H. S., Oreffo, R. O. C., Zelzer, M., Ulijn, R. V., & Dalby, M. J. (in press). Cell-controlled dynamic surfaces for skeletal stem cell growth and differentiation. Scientific Reports, 12(1), Article 8165. https://doi.org/10.1038/s41598-022-12057-z

Skeletal stem cells (SSCs, or mesenchymal stromal cells typically referred to as mesenchymal stem cells from the bone marrow) are a dynamic progenitor population that can enter quiescence, self-renew or differentiate depending on regenerative demand... Read More about Cell-controlled dynamic surfaces for skeletal stem cell growth and differentiation.

Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content (2022)
Journal Article
Taylor, M., Simoes, F., Smith, J., Genapathy, S., Canning, A., Lledos, M., Chan, W. C., Denning, C., Scurr, D. J., Steven, R. T., Spencer, S. J., Shard, A. G., Alexander, M. R., & Zelzer, M. (2022). Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content. Surface and Interface Analysis, 54(4), 417-432. https://doi.org/10.1002/sia.7052

Peptide-coated surfaces are widely employed in biomaterial design, but quantifiable correlation between surface composition and biological response is challenging due to, for example, instrumental limitations, a lack of suitable model surfaces or lim... Read More about Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content.