Outputs (2)

Frictional Effects on RNA Folding: Speed Limit and Kramers Turnover (2018)
Journal Article
Hori, N., Denesyuk, N. A., & Thirumalai, D. (2018). Frictional Effects on RNA Folding: Speed Limit and Kramers Turnover. Journal of Physical Chemistry B, 122(49), 11279-11288. https://doi.org/10.1021/acs.jpcb.8b07129

We investigated frictional effects on the folding rates of a human telomerase hairpin (hTR HP) and H-type pseudoknot from the Beet Western Yellow Virus (BWYV PK) using simulations of the Three Interaction Site (TIS) model for RNA. The heat capacity f... Read More about Frictional Effects on RNA Folding: Speed Limit and Kramers Turnover.

Monovalent ions modulate the flux through multiple folding pathways of an RNA pseudoknot (2018)
Journal Article
Roca, J., Hori, N., Baral, S., Velmurugu, Y., Narayanan, R., Narayanan, P., Thirumalai, D., & Ansari, A. (2018). Monovalent ions modulate the flux through multiple folding pathways of an RNA pseudoknot. Proceedings of the National Academy of Sciences, 115(31), E7313-E7322. https://doi.org/10.1073/pnas.1717582115

The functions of RNA pseudoknots (PKs), which are minimal tertiary structural motifs and an integral part of several ribozymes and ribonucleoprotein complexes, are determined by their structure, stability, and dynamics. Therefore, it is important to... Read More about Monovalent ions modulate the flux through multiple folding pathways of an RNA pseudoknot.