Outputs (1527)

Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences (2014)
Journal Article
Cousins, A. R., Searle, M. S., Ritson, D., Sharma, P., Stevens, M. F., & Moses, J. E. (2014). Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences. Chemical Communications, 50(96), 15202-15205. https://doi.org/10.1039/c4cc07487d

© The Royal Society of Chemistry 2014. Biophysical studies of ligand interactions with three human telomeric repeat sequences (d(AGGG(TTAGGG)n, n = 3, 7 and 11)) show that an oxazole-based 'click' ligand, which induces parallel folded quadruplexes, p... Read More about Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences.

U-III{N(SiMe(2)tBu)(2)}(3) : A Structurally Authenticated Trigonal Planar Actinide Complex (2014)
Journal Article
Goodwin, C. A., McMsater, J., Tuna, F., McInnes, E. J., Liddle, S. T., Vitorica‐Yrezabal, I. J., & Mills, D. P. (2014). U-III{N(SiMe(2)tBu)(2)}(3) : A Structurally Authenticated Trigonal Planar Actinide Complex. Chemistry - A European Journal, 20(45), 14579-14583. https://doi.org/10.1002/chem.201404864

A new pathway for heterogenization of molecular catalysts by non-covalent interactions with carbon nanoreactors (2014)
Journal Article
Schröder, M. (2014). A new pathway for heterogenization of molecular catalysts by non-covalent interactions with carbon nanoreactors. Chemistry of Materials, 26(22), https://doi.org/10.1021/cm502986d

A novel approach to heterogenisation of catalytic molecules is demonstrated using the nanoscale graphitic step-edges inside hollow graphitised carbon nanofibres (GNFs). The presence of the fullerene C60 moiety within a fullerene-salen CuII complex is... Read More about A new pathway for heterogenization of molecular catalysts by non-covalent interactions with carbon nanoreactors.

Two-directional synthesis and biological evaluation of alkaloid 5-epi-cis-275B′ (2014)
Journal Article
Procopiou, G., Aggarwal, P., Newton, A. F., Richards, D., Mellor, I. R., Harbottle, G., & Stockman, R. A. (2014). Two-directional synthesis and biological evaluation of alkaloid 5-epi-cis-275B′. Chemical Communications, 50(97), 15355-15357. https://doi.org/10.1039/c4cc07287a

© 2014 The Royal Society of Chemistry. The first total synthesis of myrmicine ant alkaloid 5-epi-cis-275B′ (4) is presented. A tandem cyclisation established the entire core of the structure in a single transformation as well as the required 2,5-anti... Read More about Two-directional synthesis and biological evaluation of alkaloid 5-epi-cis-275B′.

Intramolecular bonds resolved on a semiconductor surface (2014)
Journal Article
Sweetman, A., Jarvis, S. P., Rahe, P., Champness, N. R., Kantorovich, L., & Moriarty, P. (2014). Intramolecular bonds resolved on a semiconductor surface. Physical review B: Condensed matter and materials physics, 90(16), https://doi.org/10.1103/PhysRevB.90.165425

Noncontact atomic force microscopy (NC-AFM) is now routinely capable of obtaining submolecular resolution, readily resolving the carbon backbone structure of planar organic molecules adsorbed on metal substrates. Here we show that the same resolution... Read More about Intramolecular bonds resolved on a semiconductor surface.

Molecular simulations and visualization: introduction and overview (2014)
Journal Article
Hirst, J., Glowacki, D., & Baaden, M. (2014). Molecular simulations and visualization: introduction and overview. Faraday Discussions, 169, https://doi.org/10.1039/C4FD90024C

Here we provide an introduction and overview of current progress in the field of molecular simulation and visualization, touching on the following topics: (1) virtual and augmented reality for immersive molecular simulations; (2) advanced visualizati... Read More about Molecular simulations and visualization: introduction and overview.

Resonance-enhanced multiphoton ionization spectroscopy oflaser-ablated copper atoms (2014)
Journal Article
Andrejeva, A., Harris, J. P., & Wright, T. G. (2014). Resonance-enhanced multiphoton ionization spectroscopy oflaser-ablated copper atoms. Chemical Physics Letters, 613, https://doi.org/10.1016/j.cplett.2014.08.052

Resonance-enhanced multiphoton ionization (REMPI) spectra of laser-ablated copper atoms entrainedin a supersonic free jet expansion are reported. Depending on the ionization scheme employed, andthe conditions under which the copper atoms are produced... Read More about Resonance-enhanced multiphoton ionization spectroscopy oflaser-ablated copper atoms.

Structural chemistry of metal coordination complexes at high pressure (2014)
Journal Article
Schröder, M. (2014). Structural chemistry of metal coordination complexes at high pressure. Coordination Chemistry Reviews, 277, https://doi.org/10.1016/j.ccr.2014.04.004

The application of pressures of up to about 10 GPa may induce significant geometric, configurational, conformational and packing changes in molecular solids. This review highlights and describes recent advances in high pressure studies of coordinatio... Read More about Structural chemistry of metal coordination complexes at high pressure.

The role of copper(ii) in the aggregation of human amylin (2014)
Journal Article
Sinopoli, A., Magrì, A., Milardi, D., Pappalardo, M., Pucci, P., Flagiello, A., …Grasso, G. (2014). The role of copper(ii) in the aggregation of human amylin. Metallomics, 6(10), 1841-1852. https://doi.org/10.1039/c4mt00130c

Amylin is the 37-residue peptide hormone produced by the islet β-cells in the pancreas and the formation of amylin aggregates is strongly associated with β-cells degeneration in type 2 diabetes, as demonstrated by more than 95% of patients exhibiting... Read More about The role of copper(ii) in the aggregation of human amylin.

A Targeted Oligonucleotide Enhancer of SMN2 Exon 7 Splicing Forms Competing Quadruplex and Protein Complexes in Functional Conditions (2014)
Journal Article
Smith, L., Dickinson, R., Lucas, C., Cousins, A., Malygin, A., Weldon, C., …Eperon, I. (2014). A Targeted Oligonucleotide Enhancer of SMN2 Exon 7 Splicing Forms Competing Quadruplex and Protein Complexes in Functional Conditions. Cell Reports, 9(1), 193-205. https://doi.org/10.1016/j.celrep.2014.08.051

The use of oligonucleotides to activate the splicing of selected exons is limited by a poor understanding of the mechanisms affected. A targeted bifunctional oligonucleotide enhancer of splicing (TOES) anneals to SMN2 exon 7 and carries an exonic spl... Read More about A Targeted Oligonucleotide Enhancer of SMN2 Exon 7 Splicing Forms Competing Quadruplex and Protein Complexes in Functional Conditions.