Outputs (108)

Associations between small ruminant lentivirus infection and total milk yield and somatic cell count in a dairy sheep flock (2023)
Journal Article
Davies, P., Jones, S., Dunham, S., & Tarlinton, R. E. (2023). Associations between small ruminant lentivirus infection and total milk yield and somatic cell count in a dairy sheep flock. Veterinary Record, 192(11), Article e2731. https://doi.org/10.1002/vetr.2731

Background
Small ruminant lentiviruses (SRLVs) are lentiviruses of sheep and goats, formerly known as maedi–visna (MV) in sheep and caprine encephalitis and arthritis in goats. In sheep, SRLVs commonly cause progressive pneumonia, wasting and indura... Read More about Associations between small ruminant lentivirus infection and total milk yield and somatic cell count in a dairy sheep flock.

The importance of m6A topology in chicken embryo mRNA: a precise mapping of m6A at the conserved chicken β-actin zipcode (2023)
Journal Article
Baron, F., Zhang, M., Archer, N., Bellows, E., Knight, H. M., Welham, S., Rutland, C. S., Mongan, N. P., Hayes, C. J., Fray, R. G., & Bodi, Z. (2023). The importance of m6A topology in chicken embryo mRNA: a precise mapping of m6A at the conserved chicken β-actin zipcode. RNA, 29(6), 777-789. https://doi.org/10.1261/rna.079615.123

N6-methyladenosine (m6A) in mRNA regulates almost every stage in the mRNA life cycle, and the development of methodologies for the high-throughput detection of methylated sites in mRNA using m6A-specific methylated RNA immunoprecipitation with next-g... Read More about The importance of m6A topology in chicken embryo mRNA: a precise mapping of m6A at the conserved chicken β-actin zipcode.

Evaluation of an indwelling bolus equipped with a triaxial accelerometer for the characterisation of the diurnal pattern of bovine reticuloruminal contractions (2023)
Journal Article
Capuzzello, G., Viora, L., Borelli, E., & N. Jonsson, N. (2023). Evaluation of an indwelling bolus equipped with a triaxial accelerometer for the characterisation of the diurnal pattern of bovine reticuloruminal contractions. Journal of Dairy Research, 90(1), 9-15. https://doi.org/10.1017/s0022029923000134

This observational study aimed to describe the diurnal pattern of reticuloruminal contraction rate (RRCR) and the proportion of time spent ruminating by cattle, using two commercial devices equipped with triaxial accelerometers: an indwelling bolus (... Read More about Evaluation of an indwelling bolus equipped with a triaxial accelerometer for the characterisation of the diurnal pattern of bovine reticuloruminal contractions.

Familiarity, age, weaning and health status impact social proximity networks in dairy calves (2023)
Journal Article
Vázquez-Diosdado, J. A., Occhiuto, F., Carslake, C., & Kaler, J. (2023). Familiarity, age, weaning and health status impact social proximity networks in dairy calves. Scientific Reports, 13, Article 2275. https://doi.org/10.1038/s41598-023-29309-1

Social network analysis in dairy calves has not been widely studied, with previous studies limited by the short study duration, and low number of animals and replicates. In this study, we investigated social proximity interactions of 79 Holstein–Frie... Read More about Familiarity, age, weaning and health status impact social proximity networks in dairy calves.

Hydrogel-Based Pre-Clinical Evaluation of Repurposed FDA-Approved Drugs for AML (2023)
Journal Article
James, J. R., Curd, J., Ashworth, J. C., Abuhantash, M., Grundy, M., Seedhouse, C. H., Arkill, K. P., Wright, A. J., Merry, C. L. R., & Thompson, A. (2023). Hydrogel-Based Pre-Clinical Evaluation of Repurposed FDA-Approved Drugs for AML. International Journal of Molecular Sciences, 24(4), Article 4235. https://doi.org/10.3390/ijms24044235

In vivo models of acute myeloid leukemia (AML) are low throughput, and standard liquid culture models fail to recapitulate the mechanical and biochemical properties of the extracellular matrix-rich protective bone marrow niche that contributes to dru... Read More about Hydrogel-Based Pre-Clinical Evaluation of Repurposed FDA-Approved Drugs for AML.

Morphological and cytochemical characteristics of Varanus niloticus (Squamata, Varanidae) blood cells (2023)
Journal Article
Soliman, S. A., Abd-Elhafeez, H. H., Mohamed, N.-E., Al-Rashdi, B. M., Alghamdi, A. A., Elmansi, A., Salah, A. S., El-Gendy, S. A., Rutland, C. S., & Massoud, D. (2023). Morphological and cytochemical characteristics of Varanus niloticus (Squamata, Varanidae) blood cells. Microscopy Research and Technique, 86(5), 600-613. https://doi.org/10.1002/jemt.24298

Varanus niloticus is a lizard residing within the Varanidae family. To date no studies detailing its blood morphology and characteristics have been conducted. This study used histologically stained blood and bone marrow samples to visualize the cells... Read More about Morphological and cytochemical characteristics of Varanus niloticus (Squamata, Varanidae) blood cells.

NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma (2023)
Journal Article
Kubala, J. M., Laursen, K. B., Schreiner, R., Williams, R. M., van der Mijn, J. C., Crowley, M. J., Mongan, N. P., Nanus, D. M., Heller, D. A., & Gudas, L. J. (2023). NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma. Cancer Biology and Therapy, 24(1), Article 2170669. https://doi.org/10.1080/15384047.2023.2170669

In clear cell renal cell carcinoma (ccRCC), activation of hypoxic signaling induces NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 (NDUFA4L2) expression. Over 90% of ccRCCs exhibit overexpression of NDUFA4L2, which we previously showed... Read More about NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma.

Tilapia Lake Virus Vaccine Development: A Review on the Recent Advances (2023)
Journal Article
Kembou-Ringert, J. E., Steinhagen, D., Readman, J., Daly, J. M., & Adamek, M. (2023). Tilapia Lake Virus Vaccine Development: A Review on the Recent Advances. Vaccines, 11(2), Article 251. https://doi.org/10.3390/vaccines11020251

Tilapia tilapinevirus (or tilapia lake virus, TiLV) is a recently emerging virus associated with a novel disease affecting and decimating tilapia populations around the world. Since its initial identification, TiLV has been reported in 17 countries,... Read More about Tilapia Lake Virus Vaccine Development: A Review on the Recent Advances.

Relationships between soil and badger elemental concentrations across a heterogeneously contaminated landscape (2023)
Journal Article
Sartorius, A., Cahoon, M., Corbetta, D., Grau-Roma, L., Johnson, M. F., Sandoval Barron, E., Smallman-Raynor, M., Swift, B. M., Yon, L., Young, S., & Bennett, M. (2023). Relationships between soil and badger elemental concentrations across a heterogeneously contaminated landscape. Science of the Total Environment, 869, Article 161684. https://doi.org/10.1016/j.scitotenv.2023.161684

Understanding the links between environmental and wildlife elemental concentrations is key to help assess ecosystem functions and the potential effects of legacy pollutants. In this study, livers from 448 European badgers (Meles meles) collected acro... Read More about Relationships between soil and badger elemental concentrations across a heterogeneously contaminated landscape.

The clinical value of progesterone receptor expression in luminal breast cancer: A study of a large cohort with long-term follow-up (2023)
Journal Article
Lashen, A. G., Toss, M. S., Mongan, N. P., Green, A. R., & Rakha, E. A. (2023). The clinical value of progesterone receptor expression in luminal breast cancer: A study of a large cohort with long-term follow-up. Cancer, 129(8), 1183-1194. https://doi.org/10.1002/cncr.34655

Background: The routine assessment of progesterone receptor (PR) expression in breast cancer (BC) remains controversial. This study aimed to evaluate the role of PR expression in luminal BC, with emphasis on the definition of positivity and its progn... Read More about The clinical value of progesterone receptor expression in luminal breast cancer: A study of a large cohort with long-term follow-up.