Protein-energy malnutrition during early gestation in sheep blunts fetal renal vascular and nephron development and compromises adult renal function
(2011)
Journal Article
Lloyd, L. J., Foster, T., Rhodes, P., Rhind, S. M., & Gardner, D. S. (2011). Protein-energy malnutrition during early gestation in sheep blunts fetal renal vascular and nephron development and compromises adult renal function. Journal of Physiology, 590(2), 377-393. https://doi.org/10.1113/jphysiol.2011.220186
A nutritionally poor maternal diet can reduce nephron endowment and pre-empt premature expression of markers for chronic renal disease in the offspring. A mechanistic pathway from variation in maternal diet through altered fetal renal development to... Read More about Protein-energy malnutrition during early gestation in sheep blunts fetal renal vascular and nephron development and compromises adult renal function.