Outputs (4)

Predicting puberty in partial androgen insensitivity syndrome: use of clinical and functional androgen receptor indices (2018)
Journal Article
Lek, N., Tadokoro-Cuccaro, R., Whitchurch, J. B., Mazumder, B., Miles, H., Prentice, P., Bunch, T., Zielińska, K., Metzler, V. M., Mongan, N. P., Heery, D. M., & Hughes, I. A. (2018). Predicting puberty in partial androgen insensitivity syndrome: use of clinical and functional androgen receptor indices. EBioMedicine, 36, 401-409. https://doi.org/10.1016/j.ebiom.2018.09.047

Impact of breast cancer grade discordance on prediction of outcome (2018)
Journal Article
Rakha, E. A., Aleskandarany, M. A., Toss, M. S., Mongan, N., El-Sayed, M. E., Green, A. R., Ellis, I. O., & Dalton, L. W. (in press). Impact of breast cancer grade discordance on prediction of outcome. Histopathology, https://doi.org/10.1111/his.13709

BACKGROUND: Histological grade is an independent prognostic variable in breast cancer (BC). Previous concordance studies of BC grade have reported moderate levels of agreement; a typical finding in morphological assessment of biological variables. Th... Read More about Impact of breast cancer grade discordance on prediction of outcome.

Heterogeneity of Tumour Infiltrating Lymphocytes (TILs) in breast cancer and its prognostic significance (2018)
Journal Article
Althobiti, M., Aleskandarany, M. A., Joseph, C., Toss, M., Mongan, N., Diez-Rodriguez, M., Nolan, C. C., Ashankyty, I., Ellis, I. O., Green, A. R., & Rakha, E. A. (2018). Heterogeneity of Tumour Infiltrating Lymphocytes (TILs) in breast cancer and its prognostic significance. Histopathology, 73(6), 887-896. https://doi.org/10.1111/his.13695

Background: Tumour-infiltrating lymphocytes (TILs) in breast cancer (BC) confer prognostic and predictive information. This study aims to assess the spatial and temporal heterogeneity of TILs in BC and its relationship with immune cell subtypes.
Met... Read More about Heterogeneity of Tumour Infiltrating Lymphocytes (TILs) in breast cancer and its prognostic significance.

The dog as an animal model for bladder and urethral urothelial carcinoma: comparative epidemiology and histology (2018)
Journal Article
de Brot, S., Robinson, B. D., Scase, T., Grau‑Roma, L., Wilkinson, E., Boorjian, S. A., Gardner, D. S., & Mongan, N. P. (2018). The dog as an animal model for bladder and urethral urothelial carcinoma: comparative epidemiology and histology. Oncology Letters, 16(2), https://doi.org/10.3892/ol.2018.8837

Despite the recent approval of several novel agents for patients with metastatic urothelial carcinoma (UC), survival in this setting remains poor. As such, continued investigation into novel therapeutic options remains warranted. Pre clinical develop... Read More about The dog as an animal model for bladder and urethral urothelial carcinoma: comparative epidemiology and histology.