Outputs (16)

Antioxidant enzymes as biomarkers of Cu and Pb exposure in the ground spiders Lycosa terrestris and Pardosa birmanica (2019)
Journal Article
Elsheikha, H. M., Aziz, N., & Butt, A. (2020). Antioxidant enzymes as biomarkers of Cu and Pb exposure in the ground spiders Lycosa terrestris and Pardosa birmanica. Ecotoxicology and Environmental Safety, 190, Article 110054. https://doi.org/10.1016/j.ecoenv.2019.110054

© 2019 Elsevier Inc. Heavy metal exposure induces oxidative stress in terrestrial organisms, which they counteract via activation of antioxidant biomarkers. The present study investigated the effects of copper (Cu) and lead (Pb) on the total antioxid... Read More about Antioxidant enzymes as biomarkers of Cu and Pb exposure in the ground spiders Lycosa terrestris and Pardosa birmanica.

Assessment of bioaccumulation of cu and Pb in experimentally exposed spiders, Lycosa terrestris and Pardosa birmanica, using different exposure routes (2019)
Journal Article
Aziz, N., Butt, A., & Elsheikha, H. M. (2020). Assessment of bioaccumulation of cu and Pb in experimentally exposed spiders, Lycosa terrestris and Pardosa birmanica, using different exposure routes. Environmental Science and Pollution Research, 27, 3309–3319. https://doi.org/10.1007/s11356-019-07055-0

© 2019, Springer-Verlag GmbH Germany, part of Springer Nature. Major concerns exist regarding the environmental and human health risks caused by exposure to heavy metals. Spiders are often used as a model in ecotoxicological studies to assess soil po... Read More about Assessment of bioaccumulation of cu and Pb in experimentally exposed spiders, Lycosa terrestris and Pardosa birmanica, using different exposure routes.

Characterization of the Role of Amylo-Alpha-1,6-Glucosidase Protein in the Infectivity of Toxoplasma gondii (2019)
Journal Article
Cao, X.-Z., Wang, J.-L., Elsheikha, H. M., Li, T.-T., Sun, L.-X., Liang, Q.-L., Zhang, Z.-W., & Lin, R.-Q. (2019). Characterization of the Role of Amylo-Alpha-1,6-Glucosidase Protein in the Infectivity of Toxoplasma gondii. Frontiers in Cellular and Infection Microbiology, 9, Article 418. https://doi.org/10.3389/fcimb.2019.00418

In this study, we characterized the role of amylo-alpha-1,6-glucosidase (Aa16GL) in the biology and infectivity of Toxoplasma gondii, using Aa16GL-deficient parasites of type I RH and type II Prugniaud (Pru) strains. The subcellular localization of A... Read More about Characterization of the Role of Amylo-Alpha-1,6-Glucosidase Protein in the Infectivity of Toxoplasma gondii.

Prevalence, risk factors and genotype distribution of Toxoplasma gondii DNA in soil in China (2019)
Journal Article
Cong, W., Zhang, N.-Z., Hu, R.-S., Zou, F.-C., Zou, Y., Zhong, W.-Y., Wu, J.-J., Fallaize, C. J., Zhu, X.-Q., & Elsheikha, H. M. (2020). Prevalence, risk factors and genotype distribution of Toxoplasma gondii DNA in soil in China. Ecotoxicology and Environmental Safety, 189, Article 109999. https://doi.org/10.1016/j.ecoenv.2019.109999

Copyright © 2019 Elsevier Inc. All rights reserved. In the present study, we performed a cross-sectional survey to determine the occurrence and genotype distribution of T. gondii DNA in soil samples collected from different sources from six geographi... Read More about Prevalence, risk factors and genotype distribution of Toxoplasma gondii DNA in soil in China.

Induction and measurement of the early stage of a host-parasite interaction using a combined optical trapping and Raman microspectroscopy system (2019)
Journal Article
Sinjab, F., Elsheikha, H. M., Dooley, M., & Notingher, I. (2020). Induction and measurement of the early stage of a host-parasite interaction using a combined optical trapping and Raman microspectroscopy system. Journal of Biophotonics, 13(2), Article e201960065. https://doi.org/10.1002/jbio.201960065

© 2019 The Authors. Journal of Biophotonics published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Understanding and quantifying the temporal acquisition of host cell molecules by intracellular pathogens is fundamentally important in biology. In t... Read More about Induction and measurement of the early stage of a host-parasite interaction using a combined optical trapping and Raman microspectroscopy system.

Label-Free Quantitative Acetylome Analysis Reveals Toxoplasma gondii Genotype-Specific Acetylomic Signatures (2019)
Journal Article
Wang, Z.-X., Hu, R.-S., Zhou, C.-X., He, J.-J., M. Elsheikha, H., & Zhu, X.-Q. (2019). Label-Free Quantitative Acetylome Analysis Reveals Toxoplasma gondii Genotype-Specific Acetylomic Signatures. Microorganisms, 7(11), 1-19. https://doi.org/10.3390/microorganisms7110510

Distinct genotypic and pathogenic differences exist between Toxoplasma gondii genotypes. For example, genotype I is highly virulent, whereas genotype II and genotype III are less virulent. Moreover, Chinese 1 genotype (ToxoDB#9) is also virulent. Her... Read More about Label-Free Quantitative Acetylome Analysis Reveals Toxoplasma gondii Genotype-Specific Acetylomic Signatures.

555 Questions in Veterinary and Tropical Parasitology (2019)
Book
Elsheikha, H., & Zhu, X.-Q. (2019). 555 Questions in Veterinary and Tropical Parasitology. CAB International

Parasites are a major issue affecting animal and human health, welfare, and economic productivity. This book provides 555 questions to test your knowledge of animal and tropical parasitology, to help you study anywhere, with any amount of time. Key f... Read More about 555 Questions in Veterinary and Tropical Parasitology.

Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts (2019)
Journal Article
Zhang, X.-X., Cwiklinski, K., Hu, R.-S., Zheng, W.-B., Sheng, Z.-A., Zhang, F.-K., Elsheikha, H. M., Dalton, J. P., & Zhu, X.-Q. (2019). Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts. BMC Genomics, 20, 1-18. https://doi.org/10.1186/s12864-019-6103-5

Background
The tropical liver fluke, Fasciola gigantica causes fasciolosis, an important disease of humans and livestock. We characterized dynamic transcriptional changes associated with the development of the parasite in its two hosts, the snail in... Read More about Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts.

Serum metabolomic alterations in Beagle dogs experimentally infected with Toxocara canis (2019)
Journal Article
Zou, Y., Zheng, W.-B., Elsheikha, H. M., Liu, G.-H., Hu, M.-H., Wang, S.-L., & Zhu, X.-Q. (2019). Serum metabolomic alterations in Beagle dogs experimentally infected with Toxocara canis. Parasites and Vectors, 12(1), 1-10. https://doi.org/10.1186/s13071-019-3703-5

Background
Toxocara canis, a globally distributed roundworm, can cause debilitating disease in dogs and humans; however, little is known about the metabolomic response of the hosts to T. canis infection. There is an increasing need to understand the... Read More about Serum metabolomic alterations in Beagle dogs experimentally infected with Toxocara canis.

Sulfadiazine Sodium Ameliorates the Metabolomic Perturbation in Mice Infected with Toxoplasma gondii (2019)
Journal Article
Zhu, X.-Q., Zhou, C.-X., Liu, Q., Gan, Y., Cong, H., Elsheikha, H. M., & Chen, X.-Q. (2019). Sulfadiazine Sodium Ameliorates the Metabolomic Perturbation in Mice Infected with Toxoplasma gondii. Antimicrobial Agents and Chemotherapy, 63(10), Article e00312-19. https://doi.org/10.1128/AAC.00312-19

In this study, we analyzed the global metabolomic changes associated with Toxoplasma gondii infection in mice in the presence or absence of sulfadiazine sodium (SDZ) treatment. BALB/c mice were infected with T. gondii GT1 strain and treated orally wi... Read More about Sulfadiazine Sodium Ameliorates the Metabolomic Perturbation in Mice Infected with Toxoplasma gondii.