Maternal nutrient restriction during pregnancy differentially alters the unfolded protein response in adipose and renal tissue of obese juvenile offspring
(2008)
Journal Article
Sharkey, D., Gardner, D. S., Fainberg, H. P., Sébert, S., Bos, P., Wilson, V., Bell, R., Symonds, M. E., & Budge, H. (2009). Maternal nutrient restriction during pregnancy differentially alters the unfolded protein response in adipose and renal tissue of obese juvenile offspring. FASEB Journal, 23(5), 1314-1324. https://doi.org/10.1096/fj.08-114330
Maternal diet during pregnancy can program an offspring's risk of disease in later life. Obesity adversely alters renal and adipose tissue function, resulting in chronic kidney disease and insulin resistance, respectively, the latter associated with... Read More about Maternal nutrient restriction during pregnancy differentially alters the unfolded protein response in adipose and renal tissue of obese juvenile offspring.