Skip to main content

Research Repository

Advanced Search

Outputs (91)

Genomic insights into cardiomyopathies: a comparative cross-species review (2017)
Journal Article
Simpson, S., Rutland, P., & Rutland, C. S. (2017). Genomic insights into cardiomyopathies: a comparative cross-species review. Veterinary Sciences, 4(1), Article 19. https://doi.org/10.3390/vetsci4010019

n the global human population, the leading cause of non-communicable death is cardiovascular disease. It is predicted that by 2030, deaths attributable to cardiovascular disease will have risen to over 20 million per year. This review compares the ca... Read More about Genomic insights into cardiomyopathies: a comparative cross-species review.

Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development (2017)
Journal Article
Metzler, V. M., de Brot, S., Robinson, R. S., Jeyapalan, J. N., Rakha, E., Walton, T., …Mongan, N. P. (2017). Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development. Placenta, 56, 79-85. https://doi.org/10.1016/j.placenta.2017.02.018

The placenta and tumors share important characteristics, including a requirement to establish effective angiogenesis. In the case of the placenta, optimal angiogenesis is required to sustain the blood flow required to maintain a successful pregnancy,... Read More about Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development.

The Effects of Diet on Anatomy, Physiology and Health in the Guinea Pig (2016)
Journal Article
Witkowska, A., Price, J., Hughes, C., Smith, D., White, K., Alibhai, A., & Rutland, C. S. (2017). The Effects of Diet on Anatomy, Physiology and Health in the Guinea Pig. Journal of Animal Health and Behavioural Science, 1(1), 1-6

Given the increasing popularity of the guinea pig as a pet, it is perhaps surprising that relatively little is published as to their husbandry and dietary requirements. Indeed, a review of the literature currently available to owners, scientists and... Read More about The Effects of Diet on Anatomy, Physiology and Health in the Guinea Pig.

Multiple genetic associations with Irish wolfhound dilated cardiomyopathy (2016)
Journal Article
Simpson, S., Dunning, M. D., Brownlie, S., Patel, J., Godden, M., Cobb, M., …Rutland, C. S. (2016). Multiple genetic associations with Irish wolfhound dilated cardiomyopathy. BioMed Research International, 2016(637408), https://doi.org/10.1155/2016/6374082

Cardiac disease is a leading cause of morbidity and mortality in dogs and humans, with dilated cardiomyopathy being a large contributor to this. The Irish Wolfhound (IWH) is one of the most commonly affected breeds and one of the few breeds with gene... Read More about Multiple genetic associations with Irish wolfhound dilated cardiomyopathy.

Increased dietary protein in the second trimester of gestation increases live weight gain and carcass composition in weaner calves to 6 months of age (2016)
Journal Article
Miguel-Pacheco, G., Curtain, L., Rutland, C. S., Knott, L., Norman, S., Phillips, N., & Perry, V. (2017). Increased dietary protein in the second trimester of gestation increases live weight gain and carcass composition in weaner calves to 6 months of age. Animal, 11(6), 991-999. https://doi.org/10.1017/S1751731116002330

Genetically similar nulliparous Polled Hereford heifers from a closed pedigree herd were used to evaluate the effects of dietary protein during the first and second trimester of gestation upon fetal, placental and postnatal growth. Heifers were rando... Read More about Increased dietary protein in the second trimester of gestation increases live weight gain and carcass composition in weaner calves to 6 months of age.

Linking bone development on the caudal aspect of the distal phalanx with lameness during life (2016)
Journal Article
Newsome, R., Green, M. J., Bell, N., Chagunda, M., Mason, C., Rutland, C. S., …Huxley, J. (2016). Linking bone development on the caudal aspect of the distal phalanx with lameness during life. Journal of Dairy Science, 99(6), https://doi.org/10.3168/jds.2015-10202

Claw horn disruption lesions (CHDL; sole hemorrhage, sole ulcer, and white line disease) cause a large proportion of lameness in dairy cattle, yet their etiopathogenesis remains poorly understood. Untreated CHDL may be associated with damage to the i... Read More about Linking bone development on the caudal aspect of the distal phalanx with lameness during life.

Genetics of human and canine dilated cardiomyopathy (2015)
Journal Article
Simpson, S., Edwards, J., Ferguson-Mignan, T. F., Cobb, M., Mongan, N. P., & Rutland, C. S. (2015). Genetics of human and canine dilated cardiomyopathy. International Journal of Genomics, 2015, Article 204823. https://doi.org/10.1155/2015/204823

Cardiovascular disease is a leading cause of death in both humans and dogs. Dilated cardiomyopathy (DCM) accounts for a large number of these cases, reported to be the third most common form of cardiac disease in humans and the second most common in... Read More about Genetics of human and canine dilated cardiomyopathy.

A predictive model for canine dilated cardiomyopathy: a meta-analysis of Doberman Pinscher data (2015)
Journal Article
Simpson, S., Edwards, J., Emes, R. D., Cobb, M. A., Mongan, N. P., & Rutland, C. S. (2015). A predictive model for canine dilated cardiomyopathy: a meta-analysis of Doberman Pinscher data. PeerJ, 3, Article e842. https://doi.org/10.7717/peerj.842

Dilated cardiomyopathy is a prevalent and often fatal disease in humans and dogs. Indeed dilated cardiomyopathy is the third most common form of cardiac disease in humans, reported to affect approximately 36 individuals per 100,000 individuals. In do... Read More about A predictive model for canine dilated cardiomyopathy: a meta-analysis of Doberman Pinscher data.

Computed tomography analysis of guinea pig bone: architecture, bone thickness and dimensions throughout development. (2014)
Journal Article
Witkowska, A., Alibhai, A., Hughes, C., Price, J., Klisch, K., Sturrock, C., & Rutland, C. S. (2014). Computed tomography analysis of guinea pig bone: architecture, bone thickness and dimensions throughout development. PeerJ, 2, Article e615. https://doi.org/10.7717/peerj.615

The domestic guinea pig, Cavia aperea f. porcellus, belongs to the Caviidae family of rodents. It is an important species as a pet, a source of food and in medical research. Adult weight is achieved at 8-12 months and life expectancy is ∼5-6 years. O... Read More about Computed tomography analysis of guinea pig bone: architecture, bone thickness and dimensions throughout development..