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Outputs (39)

Very low-dose dexamethasone to facilitate extubation of preterm babies at risk of bronchopulmonary dysplasia: the MINIDEX feasibility RCT (2019)
Journal Article
Yates, H., Chiocchia, V., Linsell, L., Orsi, N., Juszczak, E., Johnson, K., …Turner, M. (2019). Very low-dose dexamethasone to facilitate extubation of preterm babies at risk of bronchopulmonary dysplasia: the MINIDEX feasibility RCT. Efficacy and Mechanism Evaluation, 6(8), 1-52. https://doi.org/10.3310/eme06080

Background: Postnatal corticosteroids are used to improve lung function and reduce the incidence of bronchopulmonary dysplasia (BPD) in preterm babies. However, corticosteroids may be associated with adverse neurodevelopment. Despite a lack of evide... Read More about Very low-dose dexamethasone to facilitate extubation of preterm babies at risk of bronchopulmonary dysplasia: the MINIDEX feasibility RCT.

Study protocol for a randomised controlled trial assessing the clinical and cost-effectiveness of the Journeying through Dementia (JtD) intervention compared to usual care (2019)
Journal Article
Wright, J., Foster, A., Cooper, C., SPRANGE, K., Walters, S., Berry, K., …Mountain, G. (2019). Study protocol for a randomised controlled trial assessing the clinical and cost-effectiveness of the Journeying through Dementia (JtD) intervention compared to usual care. BMJ Open, 9(9), Article e029207. https://doi.org/10.1136/bmjopen-2019-029207

Introduction: Services are being encouraged to provide postdiagnostic treatment to those with dementia but the availability of evidence-based interventions following diagnosis has not kept pace with increase in demand. To address this need, the Journ... Read More about Study protocol for a randomised controlled trial assessing the clinical and cost-effectiveness of the Journeying through Dementia (JtD) intervention compared to usual care.

The WHEAT pilot trial - WithHolding Enteral feeds around packed red cell Transfusion to prevent necrotising enterocolitis in preterm neonates: A multicentre, electronic patient record (EPR), randomised controlled point-of-care pilot trial (2019)
Journal Article
Gale, C., Modi, N., Jawad, S., Culshaw, L., Dorling, J., Bowler, U., …Juszczak, E. (2019). The WHEAT pilot trial - WithHolding Enteral feeds around packed red cell Transfusion to prevent necrotising enterocolitis in preterm neonates: A multicentre, electronic patient record (EPR), randomised controlled point-of-care pilot trial. BMJ Open, 9(9), Article e033543. https://doi.org/10.1136/bmjopen-2019-033543

Introduction Necrotising enterocolitis (NEC) is a potentially devastating neonatal disease. A temporal association between red cell transfusion and NEC is well described. Observational data suggest that withholding enteral feeds around red cell trans... Read More about The WHEAT pilot trial - WithHolding Enteral feeds around packed red cell Transfusion to prevent necrotising enterocolitis in preterm neonates: A multicentre, electronic patient record (EPR), randomised controlled point-of-care pilot trial.

Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial (2019)
Journal Article
Chappell, L. C., Brocklehurst, P., Green, M. E., Hunter, R., Hardy, P., Juszczak, E., …Wu, P. (2019). Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial. Lancet, 394(10204), 1181-1190. https://doi.org/10.1016/s0140-6736%2819%2931963-4

© 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Background: In women with late preterm pre-eclampsia, the optimal time to initiate delivery is unclear because limitation of maternal disease... Read More about Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial.

Responsiveness and Minimal Important Change for Pain and Disability Outcome Measures in Pregnancy-Related Low Back and Pelvic Girdle Pain (2019)
Journal Article
Ogollah, R., Bishop, A., Lewis, M., Grotle, M., & Foster, N. E. (2019). Responsiveness and Minimal Important Change for Pain and Disability Outcome Measures in Pregnancy-Related Low Back and Pelvic Girdle Pain. Physical Therapy, 99(11), 1551-1561. https://doi.org/10.1093/ptj/pzz107

Background Pregnancy-related low back pain and pelvic girdle pain (LBP/PGP) are common and negatively impact the lives of many pregnant women. Several patient-based outcome instruments measure treatment effect but there is no consensus about which m... Read More about Responsiveness and Minimal Important Change for Pain and Disability Outcome Measures in Pregnancy-Related Low Back and Pelvic Girdle Pain.

Randomised trial of cord clamping at very preterm birth: outcomes at 2 years (2019)
Journal Article
Armstrong-Buisseret, L., Powers, K., Dorling, J., Bradshaw, L., Johnson, S., Mitchell, E., & Duley, L. (2020). Randomised trial of cord clamping at very preterm birth: outcomes at 2 years. Archives of Disease in Childhood. Fetal and Neonatal Edition, 105(3), 292-298. https://doi.org/10.1136/archdischild-2019-316912

Objective: To report outcomes at 2 years corrected age for children of women recruited to a trial comparing alternative policies for timing of cord clamping and immediate neonatal care at very preterm birth. Design: Parallel group randomised (1:1... Read More about Randomised trial of cord clamping at very preterm birth: outcomes at 2 years.

Non-traditional support workers delivering a brief psychosocial intervention for older people with anxiety and depression: the NOTEPAD feasibility study (2019)
Journal Article
Burroughs, H., Bartlam, B., Bullock, P., Lovell, K., Ogollah, R., Ray, M., …Chew-Graham, C. A. (2019). Non-traditional support workers delivering a brief psychosocial intervention for older people with anxiety and depression: the NOTEPAD feasibility study. Health Services and Delivery Research, 7(25), 1-120. https://doi.org/10.3310/hsdr07250

Cochrane systematic review and meta-analysis of botulinum toxin for the prevention of migraine (2019)
Journal Article
Herd, C. P., Tomlinson, C. L., Rick, C., Scotton, W. J., Edwards, J., Ives, N. J., …Sinclair, A. (2019). Cochrane systematic review and meta-analysis of botulinum toxin for the prevention of migraine. BMJ Open, 9(7), Article e027953. https://doi.org/10.1136/bmjopen-2018-027953

Objectives To assess the effects of botulinum toxin for prevention of migraine in adults. Design Systematic review and meta-analysis. Data sources CENTRAL, MEDLINE, Embase and trial registries. Eligibility criteria We included randomised contr... Read More about Cochrane systematic review and meta-analysis of botulinum toxin for the prevention of migraine.

Subgrouping patients with sciatica in primary care for matched care pathways: development of a subgrouping algorithm (2019)
Journal Article
Konstantinou, K., Dunn, K. M., van der Windt, D., Ogollah, R., Jasani, V., Foster, N. E., & SCOPiC study team, . (2019). Subgrouping patients with sciatica in primary care for matched care pathways: development of a subgrouping algorithm. BMC Musculoskeletal Disorders, 20, 1-9. https://doi.org/10.1186/s12891-019-2686-x

Background Sciatica is a painful condition managed by a stepped care approach for most patients. Currently, there are no decision-making tools to guide matching care pathways for patients with sciatica without evidence of serious pathology, early in... Read More about Subgrouping patients with sciatica in primary care for matched care pathways: development of a subgrouping algorithm.

Eicosapentaenoic acid and/or aspirin for preventing colorectal adenomas during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme: the seAFOod RCT (2019)
Journal Article
Hull, M. A., Sprange, K., Hepburn, T., Tan, W., Shafayat, A., Rees, C. J., …Montgomery, A. A. (2019). Eicosapentaenoic acid and/or aspirin for preventing colorectal adenomas during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme: the seAFOod RCT. Efficacy and Mechanism Evaluation, 6(4), 1-154. https://doi.org/10.3310/eme06040