Outputs (577)

The importance of protein sources to support muscle anabolism in cancer: An expert group opinion (2021)
Journal Article
Ford, K. L., Arends, J., Atherton, P. J., Engelen, M. P., Gonçalves, T. J., Laviano, A., Lobo, D. N., Phillips, S. M., Ravasco, P., Deutz, N. E., & Prado, C. M. (2022). The importance of protein sources to support muscle anabolism in cancer: An expert group opinion. Clinical Nutrition, 41(1), 192-201. https://doi.org/10.1016/j.clnu.2021.11.032

This opinion paper presents a short review of the potential impact of protein on muscle anabolism in cancer, which is associated with better patient outcomes. Protein source is a topic of interest for patients and clinicians, partly due to recent emp... Read More about The importance of protein sources to support muscle anabolism in cancer: An expert group opinion.

Management of post-acute COVID-19 patients in geriatric rehabilitation: EuGMS guidance (2021)
Journal Article
van Haastregt, J. C., Everink, I. H. J., Schols, J. M. G. A., Grund, S., Gordon, A. L., Poot, E. P., Martin, F. C., O’Neill, D., Petrovic, M., Bachmann, S., van Balen, R., van Dam van Isselt, L., Dockery, F., Holstege, M. S., Landi, F., Pérez, L. M., Roquer, E., Smalbrugge, M., & Achterberg, W. P. (2022). Management of post-acute COVID-19 patients in geriatric rehabilitation: EuGMS guidance. European Geriatric Medicine, 13(1), 291-304. https://doi.org/10.1007/s41999-021-00575-4

Purpose: To describe a guidance on the management of post-acute COVID 19 patients in geriatric rehabilitation. Methods: The guidance is based on guidelines for post-acute COVID-19 geriatric rehabilitation developed in the Netherlands, updated with re... Read More about Management of post-acute COVID-19 patients in geriatric rehabilitation: EuGMS guidance.

Feasibility RCT of neuromuscular electrical stimulation; an Intervention to Maintain and improve neuroMuscular function during periods of Immobility (IMMI): Protocol (2021)
Preprint / Working Paper
Gladman, J., Aloraibi, S., Greenhaff, P., Piasecki, M., Phillips, B., Atherton, P., Masud, T., Sahota, O., Logan, P., Booth, V., Robinson, K., Lunt, E., Godfrey, D., Caswell, A., Kerr, M., Ollivere, B., & Gordon, A. Feasibility RCT of neuromuscular electrical stimulation; an Intervention to Maintain and improve neuroMuscular function during periods of Immobility (IMMI): Protocol

East Midlands Research into Ageing Network (EMRAN) is a research collaboration across the East Midlands to facilitate collaborative applied clinical research into ageing and the care of older people. EMRAN was set up by NIHR CLAHRC East Midlands and... Read More about Feasibility RCT of neuromuscular electrical stimulation; an Intervention to Maintain and improve neuroMuscular function during periods of Immobility (IMMI): Protocol.

Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol (2021)
Preprint / Working Paper
Usman, A., Lewis, S., Clarkson, P., & Gordon, A. Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol

Introduction
There is a high prevalence of frailty and cognitive impairment within care home population. These wide-ranging experiences and needs impact on residents’ quality of life. Therefore, measuring Quality of Life (QOL) in residents as part... Read More about Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol.

GPs’ involvement to improve care quality in care homes in the UK: a realist review (2021)
Journal Article
Chadborn, N. H., Devi, R., Williams, C., Sartain, K., Goodman, C., & Gordon, A. L. (2021). GPs’ involvement to improve care quality in care homes in the UK: a realist review. Health Services and Delivery Research, 9(20), 1-76. https://doi.org/10.3310/hsdr09200

Background
Organising health-care services for residents living in care homes is an important area of development in the UK and elsewhere. Medical care is provided by general practitioners in the UK, and the unique arrangement of the NHS means that... Read More about GPs’ involvement to improve care quality in care homes in the UK: a realist review.

Anti-reflux medication use in preterm infants (2021)
Journal Article
Binti Abdul Hamid, H., Szatkowski, L., Budge, H., & Ojha, S. (2022). Anti-reflux medication use in preterm infants. Pediatric Research, 92, 520-525. https://doi.org/10.1038/s41390-021-01821-y

Background: Current recommendations do not support the use of anti-reflux medications to treat gastro-oesophageal reflux disease (GORD) among preterm infants. Objective: To describe the prevalence of GORD and the use of anti-reflux medications amongs... Read More about Anti-reflux medication use in preterm infants.

Green Tea Extract Concurrent with an Oral Nutritional Supplement Acutely Enhances Muscle Microvascular Blood Flow without Altering Leg Glucose Uptake in Healthy Older Adults (2021)
Journal Article
Din, U. S. U., Sian, T. S., Deane, C. S., Smith, K., Gates, A., Lund, J. N., Williams, J. P., Rueda, R., Pereira, S. L., Atherton, P. J., & Phillips, B. E. (2021). Green Tea Extract Concurrent with an Oral Nutritional Supplement Acutely Enhances Muscle Microvascular Blood Flow without Altering Leg Glucose Uptake in Healthy Older Adults. Nutrients, 13(11), Article 3895. https://doi.org/10.3390/nu13113895

Postprandial macro-and microvascular blood flow and metabolic dysfunction manifest with advancing age, so vascular transmuting interventions are desirable. In this randomised, singleblind, placebo-controlled, crossover trial, we investigated the impa... Read More about Green Tea Extract Concurrent with an Oral Nutritional Supplement Acutely Enhances Muscle Microvascular Blood Flow without Altering Leg Glucose Uptake in Healthy Older Adults.

Development and validation of a prognostic model for leflunomide discontinuation with abnormal blood tests during long-term treatment: cohort study using data from the Clinical Practice Research Datalink Gold and Aurum (2021)
Journal Article
Nakafero, G., Grainge, M. J., Card, T., Taal, M. W., Aithal, G. P., Zhang, W., Doherty, M., Fox, C. P., Mallen, C. D., & Abhishek, A. (2022). Development and validation of a prognostic model for leflunomide discontinuation with abnormal blood tests during long-term treatment: cohort study using data from the Clinical Practice Research Datalink Gold and Aurum. Rheumatology, 61(7), 2783-2791. https://doi.org/10.1093/rheumatology/keab790

OBJECTIVE: To develop and validate a prognostic model for LEF discontinuation with abnormal blood test results. METHODS: Data from the Clinical Practice Research Datalink Gold and Aurum were used for model development and external validation, respect... Read More about Development and validation of a prognostic model for leflunomide discontinuation with abnormal blood tests during long-term treatment: cohort study using data from the Clinical Practice Research Datalink Gold and Aurum.

Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections (2021)
Journal Article
Bath, P. M., Coleman, C. M., Gordon, A. L., Lim, W. S., & Webb, A. J. (2021). Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections. F1000Research, 10, 1-39. https://doi.org/10.12688/f1000research.51270.2

Although the antimicrobial potential of nitric oxide (NO) is widely published, it is little used clinically. NO is a key signalling molecule modulating vascular, neuronal, inflammatory and immune responses. Endogenous antimicrobial activity is largel... Read More about Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections.

Cardiovascular risk profiles: A cross-sectional study evaluating the generalizability of the glucagon-like peptide-1 receptor agonist cardiovascular outcome trials REWIND, LEADER and SUSTAIN-6 to the real-world type 2 diabetes population in the United Kingdom (2021)
Journal Article
Webb, J., Mount, J., von Arx, L. B., Rachman, J., Spanopoulos, D., Wood, R., Tritton, T., Massey, O., & Idris, I. (2022). Cardiovascular risk profiles: A cross-sectional study evaluating the generalizability of the glucagon-like peptide-1 receptor agonist cardiovascular outcome trials REWIND, LEADER and SUSTAIN-6 to the real-world type 2 diabetes population in the United Kingdom. Diabetes, Obesity and Metabolism, 24(2), 289-295. https://doi.org/10.1111/dom.14580

Aims: To determine the proportion of UK patients with type 2 diabetes (T2D) who meet the cardiovascular (CV) or combined CV/core eligibility criteria used for the CV outcome trials (CVOTs) of UK-marketed glucagon-like peptide-1 receptor agonists (GLP... Read More about Cardiovascular risk profiles: A cross-sectional study evaluating the generalizability of the glucagon-like peptide-1 receptor agonist cardiovascular outcome trials REWIND, LEADER and SUSTAIN-6 to the real-world type 2 diabetes population in the United Kingdom.