Outputs (577)

The impact of endometrioma and its surgical treatment on ovarian reserve and reproductive performance (2015)
Book Chapter
Amer, S. A. K. (2015). The impact of endometrioma and its surgical treatment on ovarian reserve and reproductive performance. In M. Metwally, & T.-C. Li (Eds.), Reproductive Surgery in Assisted Conception (43-57). Springer London. https://doi.org/10.1007/978-1-4471-4953-8_5

Endometriomas, which are commonly encountered in women presenting with subfertility, usually represent a dilemma to the Reproductive Specialist. Surgery remains the only effective treatment for endometriomas larger than three cm in diameter. National... Read More about The impact of endometrioma and its surgical treatment on ovarian reserve and reproductive performance.

Laparoscopic ovarian drilling (2015)
Book Chapter
Amer, S. A. K. (2015). Laparoscopic ovarian drilling. In M. Metwally, & T.-C. Li (Eds.), Reproductive Surgery in Assisted Conception (61-71). Springer London. https://doi.org/10.1007/978-1-4471-4953-8_6

Laparoscopic ovarian drilling has been widely accepted as the second line of choice for induction of ovulation in CC-resistant PCOS women in preference to gonadotrophin therapy. In addition to its proven efficacy, LOD offers several advantages over g... Read More about Laparoscopic ovarian drilling.

Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications (2014)
Journal Article
Jones, K., Doleman, B., Scott, S., Lund, J. N., & Williams, J. P. (2015). Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications. Colorectal Disease, 17(1), Article O20-O26. https://doi.org/10.1111/codi.12805

Aim

Radiologically assessed muscle mass has been suggested as a surrogate marker of functional status and frailty and may predict patients at risk of postoperative complications. We hypothesize that sarcopenia negatively impacts on postoperative r... Read More about Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications.

Access to medicines by child refugees in the East Midlands region of England: a cross-sectional study (2014)
Journal Article
Alkahtani, S. A., Cherrill, J., Millward, C., Grayson, K., Hilliam, R., Sammons, H., & Choonara, I. (2014). Access to medicines by child refugees in the East Midlands region of England: a cross-sectional study. BMJ Open, 4, Article e006421. https://doi.org/10.1136/bmjopen-2014-006421

Objectives: To explore access to primary healthcare and drug therapy by refugee children in the East Midlands region of England.
Design: Interviews with refugees with children and a control group of British parents with children.
Setting: East Midl... Read More about Access to medicines by child refugees in the East Midlands region of England: a cross-sectional study.

A dose- rather than delivery profile-dependent mechanism regulates the "muscle-full" effect in response to oral essential amino acid intake in young men (2014)
Journal Article
Mitchell, W. K., Phillips, B. E., Williams, J. P., Rankin, D., Lund, J. N., Smith, K., & Atherton, P. J. (2015). A dose- rather than delivery profile-dependent mechanism regulates the "muscle-full" effect in response to oral essential amino acid intake in young men. Journal of Nutrition, 145(2), https://doi.org/10.3945/jn.114.199604

Background: The anabolic response of skeletal muscle to essential amino acids (EAAs) is dose dependent, maximal at modest doses, and short lived, even with continued EAA availability, a phenomenon termed “muscle-full.” However, the effect of EAA inge... Read More about A dose- rather than delivery profile-dependent mechanism regulates the "muscle-full" effect in response to oral essential amino acid intake in young men.

Cannabinoids in experimental stroke: a systematic review and meta-analysis (2014)
Journal Article
England, T. J., Hind, W. H., Rasid, N. A., & O'Sullivan, S. (2015). Cannabinoids in experimental stroke: a systematic review and meta-analysis. Journal of Cerebral Blood Flow and Metabolism, 35(3), https://doi.org/10.1038/jcbfm.2014.218

Cannabinoids (CBs) show promise as neuroprotectants with some agents already licensed in humans for other conditions. We systematically reviewed CBs in preclinical stroke to guide further experimental protocols. We selected controlled studies assessi... Read More about Cannabinoids in experimental stroke: a systematic review and meta-analysis.

An evaluation of POSSUM and P-POSSUM scoring in predicting post-operative mortality in a level 1 critical care setting (2014)
Journal Article
Scott, S., Lund, J. N., Gold, S., Elliott, R., Vater, M., Chakrabarty, M. P., …Williams, J. P. (2014). An evaluation of POSSUM and P-POSSUM scoring in predicting post-operative mortality in a level 1 critical care setting. BMC Anesthesiology, 14(1), Article 104. https://doi.org/10.1186/1471-2253-14-104

Background

POSSUM and P-POSSUM are used in the assessment of outcomes in surgical patients. Neither scoring systems’ accuracy has been established where a level 1 critical care facility (level 1 care ward) is available for perioperative care. We c... Read More about An evaluation of POSSUM and P-POSSUM scoring in predicting post-operative mortality in a level 1 critical care setting.

Methods to Assess Subcellular Compartments of Muscle in C. elegans (2014)
Journal Article
Gaffney, C. J., Bass, J. J., Barratt, T. F., & Szewczyk, N. J. (in press). Methods to Assess Subcellular Compartments of Muscle in C. elegans. Journal of Visualized Experiments, Article e52043. https://doi.org/10.3791/52043

Skeletal muscle is essential for locomotion and is the bodies’ main protein store. Muscle health measurements within C. elegans are described. Prospective changes to muscle structure and function are assessed using localized GFP and cationic dyes.

One-third of patients fail to return to work 1 year after surgery for colorectal cancer (2014)
Journal Article
Bhalla, A., Williams, J. P., Hurst, N., Speake, W., Tierney, G., Tou, S., & Lund, J. N. (2014). One-third of patients fail to return to work 1 year after surgery for colorectal cancer. Techniques in Coloproctology, 18(12), https://doi.org/10.1007/s10151-014-1232-y

Background

Achieving full recovery after colorectal cancer surgery means a return to normal physical and psychological health and to a normal social life. Recovery data focusses on time to discharge rather than longer term functionality including... Read More about One-third of patients fail to return to work 1 year after surgery for colorectal cancer.

Valproic acid and fatalities in children: a review of individual case safety reports in VigiBase (2014)
Journal Article
Star, K., Edwards, I. R., & Choonara, I. (2014). Valproic acid and fatalities in children: a review of individual case safety reports in VigiBase. PLoS ONE, 9(10), Article e108970. https://doi.org/10.1371/journal.pone.0108970

Introduction

Valproic acid is an effective first line drug for the treatment of epilepsy. Hepatotoxicity is a rare and potentially fatal adverse reaction for this medicine.
Objective

Firstly to characterise valproic acid reports on children wi... Read More about Valproic acid and fatalities in children: a review of individual case safety reports in VigiBase.