Outputs (577)

The impact of delivery profile of essential amino acids upon skeletal muscle protein synthesis in older men: clinical efficacy of pulse vs. bolus supply (2015)
Journal Article
Mitchell, W. K., Phillips, B. E., Williams, J. P., Rankin, D., Lund, J. N., Wilkinson, D. J., Smith, K., & Atherton, P. J. (2015). The impact of delivery profile of essential amino acids upon skeletal muscle protein synthesis in older men: clinical efficacy of pulse vs. bolus supply. AJP - Endocrinology and Metabolism, 309(5), Article E450-E457. https://doi.org/10.1152/ajpendo.00112.2015

Essential amino acids (EAA) are responsible for skeletal muscle anabolic effects after nutrient intake. The pattern of appearance of EAA in blood, e.g., after intake of “slow” or “fast” protein sources or in response to grazing vs. bolus feeding patt... Read More about The impact of delivery profile of essential amino acids upon skeletal muscle protein synthesis in older men: clinical efficacy of pulse vs. bolus supply.

Why do young children die in the UK?: a comparison with Sweden (2015)
Journal Article
with Sweden. Archives of Disease in Childhood, 100, https://doi.org/10.1136/archdischild-2014-308059

Background
The UK has a high child mortality rate, whereas Sweden’s is lower (under-five mortality rates of five and three, respectively, in 2011).We therefore wished to compare causes of death in young children aged <5 years in the two countries....

Day-case closure of ileostomy: feasible, safe and efficient (2015)
Journal Article
Bhalla, A., Peacock, O., Tierney, G., Tou, S., Hurst, N., Speake, W., Williams, J. P., & Lund, J. N. (2015). Day-case closure of ileostomy: feasible, safe and efficient. Colorectal Disease, 17(9), https://doi.org/10.1111/codi.12961

Aim

Over 5000 loop ileostomy closures were performed in the UK in 2013 with a median inpatient stay of 5 days. Previously we have successfully implemented a 23-h protocol for loop ileostomy closure which was modified for same-day discharge. We pre... Read More about Day-case closure of ileostomy: feasible, safe and efficient.

Internal comparison between deuterium oxide (D2O) and L-[ring-13C6] phenylalanine for acute measurement of muscle protein synthesis in humans (2015)
Journal Article
Smith, K., Cegielski, J., Wilkinson, D., Phillips, B., Boereboom, C., Lund, J., & Atherton, P. (2015). Internal comparison between deuterium oxide (D2O) and L-[ring-13C6] phenylalanine for acute measurement of muscle protein synthesis in humans. Physiological Reports, 3(7), Article e12433. https://doi.org/10.14814/phy2.12433

Stable isotope tracer methodologies are becoming increasingly widespread in metabolic research; yet a number of factors restrict their implementation, such as, i.v infusions, multiple cannulae, tissue samples, and significant cost. We recently valida... Read More about Internal comparison between deuterium oxide (D2O) and L-[ring-13C6] phenylalanine for acute measurement of muscle protein synthesis in humans.

Skeletal muscle homeostasis and plasticity in youth and ageing: impact of nutrition and exercise (2015)
Journal Article
Brook, M. S., Wilkinson, D. J., Phillips, B. E., Perez-Schindler, J., Philp, A., Smith, K., & Atherton, P. J. (2016). Skeletal muscle homeostasis and plasticity in youth and ageing: impact of nutrition and exercise. Acta Physiologica, 216(1), 15-41. https://doi.org/10.1111/apha.12532

Cannabidiol causes endothelium-dependent vasorelaxation of human mesenteric arteries via CB1 activation (2015)
Journal Article
Stanley, C., Hind, W., Tufarelli, C., & O'SULLIVAN, S. (2015). Cannabidiol causes endothelium-dependent vasorelaxation of human mesenteric arteries via CB1 activation. Cardiovascular Research, 107(4), 568-578. https://doi.org/10.1093/cvr/cvv179

Study investigating the role of skeletal muscle mass estimation in metastatic spinal cord compression (2015)
Journal Article
Gakhar, H., Dhillon, A., Blackwell, J., Hussain, K., Bommireddy, R., Klezl, Z., & Williams, J. (2015). Study investigating the role of skeletal muscle mass estimation in metastatic spinal cord compression. European Spine Journal, 24(10), 2150-2155. https://doi.org/10.1007/s00586-015-4050-7

Background

Age-related loss of functional muscle mass is associated with reduced functional ability and life expectancy. In disseminated cancer, age-related muscle loss may be exacerbated by cachexia and poor nutritional intake, increasing functio... Read More about Study investigating the role of skeletal muscle mass estimation in metastatic spinal cord compression.

P-699, Androgen synthesis in peripheral adipose tissue: the role of insulin and luteinizing hormone in women with polycystic ovarian syndrome (2015)
Presentation / Conference Contribution
Amer, S., Alzanati, N., & Khan, R. P-699, Androgen synthesis in peripheral adipose tissue: the role of insulin and luteinizing hormone in women with polycystic ovarian syndrome

O-221, Double blind cross-over randomized controlled trial comparing letrozole versus clomiphene citrate for ovulation induction in women with polycystic ovarian syndrome (2015)
Presentation / Conference Contribution
Amer, S., Amith, J., Mahran, A., Fox, P., & Fakis, A. O-221, Double blind cross-over randomized controlled trial comparing letrozole versus clomiphene citrate for ovulation induction in women with polycystic ovarian syndrome

A prospective study of adverse drug reactions to antiepileptic drugs in children (2015)
Journal Article
Anderson, M., Egunsola, O., Cherrill, J., Millward, C., Fakis, A., & Choonara, I. (2015). A prospective study of adverse drug reactions to antiepileptic drugs in children. BMJ Open, 5, Article e008298. https://doi.org/10.1136/bmjopen-2015-008298

Objectives To prospectively determine the nature and rate of adverse drug reactions (ADRs) in children on antiepileptic drugs (AEDs) and to prospectively evaluate the effect of AEDs on behaviour.

Setting A single centre prospective observational s... Read More about A prospective study of adverse drug reactions to antiepileptic drugs in children.