Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications

Jones, K.I.; Doleman, Brett; Scott, S.D.; Lund, Jonathan N.; Williams, John P.

Abstract

Aim

Radiologically assessed muscle mass has been suggested as a surrogate marker of functional status and frailty and may predict patients at risk of postoperative complications. We hypothesize that sarcopenia negatively impacts on postoperative recovery and is predictive of complications.
Method

One hundred patients undergoing elective resection for colorectal carcinoma were included in this study. Lean muscle mass was estimated by measuring the cross-sectional area of the psoas muscle at the level of the third lumbar vertebra identified on a preoperative CT scan, normalizing for patient height. Perioperative morbidity was scored according to the Clavien–Dindo classification. All statistical data analyses were carried out using the Statistical Package for the Social Sciences (SPSS) version 20.0.
Results

Fifteen per cent of patients were identified as sarcopenic. There were no deaths in the study group. Sarcopenia was associated with a significantly increased risk of developing major complications (Grade 3 or greater, OR = 5.41, 95% CI: 1.45–20.15, P = 0.01). Sarcopenia did not predict length of stay, critical care dependency or time to mobilization.
Conclusion

Sarcopenia, as a marker of frailty, is an important risk factor in surgical patients but difficult to estimate using bedside testing. CT scans, performed for preoperative staging, provide an opportunity to quantify lean muscle mass without additional cost or exposure to radiation and eliminate the inconvenience of further investigations.

Citation

Jones, K., Doleman, B., Scott, S., Lund, J. N., & Williams, J. P. (2015). Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications. Colorectal Disease, 17(1), Article O20-O26. https://doi.org/10.1111/codi.12805

• Journal Article Type: Article
• Acceptance Date: Sep 6, 2014
• Online Publication Date: Dec 23, 2014
• Publication Date: Jan 1, 2015
• Deposit Date: Aug 1, 2017
• Journal: Colorectal Disease
• Print ISSN: 1462-8910
• Electronic ISSN: 1463-1318
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 17
• Issue: 1
• Article Number: O20-O26
• DOI: https://doi.org/10.1111/codi.12805
• Keywords: Sarcopenia; complications; computed tomography
• Public URL: https://nottingham-repository.worktribe.com/output/985378
• Publisher URL: http://onlinelibrary.wiley.com/doi/10.1111/codi.12805/abstract
• Contract Date: Aug 1, 2017