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Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism (2013)
Journal Article
Wilkinson, D., Hossain, T., Hill, D., Phillips, B., Crossland, H., Williams, J., …Atherton, P. (2013). Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism. Journal of Physiology, 591(11), https://doi.org/10.1113/jphysiol.2013.253203

Maintenance of skeletal muscle mass is contingent upon the dynamic equilibrium (fasted losses–fed gains) in protein turnover. Of all nutrients, the single amino acid leucine (Leu) possesses the most marked anabolic characteristics in acting as a trig... Read More about Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism.

Natural history of skeletal muscle mass changes in chronic kidney disease stage 4 and 5 patients: an observational study (2013)
Journal Article
John, S. G., Sigrist, M. K., Taal, M. W., & McIntyre, C. W. (2013). Natural history of skeletal muscle mass changes in chronic kidney disease stage 4 and 5 patients: an observational study. PLoS ONE, 8(5), Article e65372. https://doi.org/10.1371/journal.pone.0065372

Cross-sectional studies in dialysis demonstrate muscle wasting associated with loss of function, increased morbidity and mortality. The relative drivers are poorly understood. There is a paucity of data regarding interval change in muscle in pre-dial... Read More about Natural history of skeletal muscle mass changes in chronic kidney disease stage 4 and 5 patients: an observational study.

Molecular ageing of alpha- and beta-synucleins: protein damage and repair mechanisms (2013)
Journal Article
Vigneswara, V., Cass, S., Wayne, D., Bolt, E. L., Ray, D. E., & Carter, W. (2013). Molecular ageing of alpha- and beta-synucleins: protein damage and repair mechanisms. PLoS ONE, 8(4), Article e61442. https://doi.org/10.1371/journal.pone.0061442

Abnormal α-synuclein aggregates are hallmarks of a number of neurodegenerative diseases. Alpha synuclein and β-synucleins are susceptible to post-translational modification as isoaspartate protein damage, which is regulated in vivo by the action of t... Read More about Molecular ageing of alpha- and beta-synucleins: protein damage and repair mechanisms.

Wide intra- and inter-country variability in drug use and dosage in very-low-birth-weight newborns with severe infections (2013)
Journal Article
Pandolfini, C., Kaguelidou, F., Sequi, M., Jacqz-Aigrain, E., Choonara, I., Turner, M. A., …Bonita, M. (2013). Wide intra- and inter-country variability in drug use and dosage in very-low-birth-weight newborns with severe infections. European Journal of Clinical Pharmacology, 69(4), https://doi.org/10.1007/s00228-012-1415-2

Purpose: To describe the use of ciprofloxacin and fluconazole for the treatment of sepsis in European neonatal intensive care units (NICUs) in order to better orient research aimed at acquiring essential knowledge in this critical area.
Methods: The... Read More about Wide intra- and inter-country variability in drug use and dosage in very-low-birth-weight newborns with severe infections.

Invasive lobular carcinoma arising in accessory breast tissue (2013)
Journal Article
Devine, C., Courtney, C.-A., Deb, R., & Agrawal, A. (2013). Invasive lobular carcinoma arising in accessory breast tissue. World Journal of Surgical Oncology, 11(47), Article 47. https://doi.org/10.1186/1477-7819-11-47

Background: Lobular carcinoma in accessory breast tissue is a rare occurrence. We present such a case in a 61-year-old woman.

Case presentation: A skin nodule in the axillary skin on excision biopsy revealed invasive lobular carcinoma.

Conclus... Read More about Invasive lobular carcinoma arising in accessory breast tissue.

An investigation into the spiritual needs of neuro-oncology patients from a nurse perspective (2013)
Journal Article
Nixon, A. V., Narayanasamy, A., & Penny, V. (2013). An investigation into the spiritual needs of neuro-oncology patients from a nurse perspective. BMC Nursing, 12, Article 2. https://doi.org/10.1186/1472-6955-12-2

Background: Spiritual needs of cancer patients should be assessed and discussed by healthcare professionals. Neurosurgical nurses need to be able to assess and support neuro-oncology patients with their spiritual needs from diagnosis and throughout t... Read More about An investigation into the spiritual needs of neuro-oncology patients from a nurse perspective.

Intestinal ischemia following laparoscopic surgery: a case series (2013)
Journal Article
Al-Khyatt, W., Thomas, J. D., Humes, D. J., & Lobo, D. N. (2013). Intestinal ischemia following laparoscopic surgery: a case series. Journal of Medical Case Reports, 7(25), Article 25. https://doi.org/10.1186/1752-1947-7-25

Introduction: Intestinal ischemia is a rare complication of laparoscopic surgery. Its prognosis depends on a high
index of suspicion and effective early treatment.
Case presentation: In the present report, we describe three cases where intestinal i... Read More about Intestinal ischemia following laparoscopic surgery: a case series.

Acute intestinal obstruction secondary to left paraduodenal hernia: a case report and literature review (2013)
Journal Article
Al-Khyatt, W., Aggarwal, S., Birchall, J., & Rowlands, T. E. (2013). Acute intestinal obstruction secondary to left paraduodenal hernia: a case report and literature review. World Journal of Emergency Surgery, 8(5), Article 5. https://doi.org/10.1186/1749-7922-8-5

Introduction: An internal hernia is a protrusion of bowel through a normal or abnormal orifice in the peritoneum
or mesentery. Although they are considered as a rare cause of intestinal obstruction, paraduodenal hernias are the
most common type of... Read More about Acute intestinal obstruction secondary to left paraduodenal hernia: a case report and literature review.

Medication errors in the Middle East countries: a systematic review of the literature (2013)
Journal Article
Alsulami, Z., Conroy, S., & Choonara, I. (2013). Medication errors in the Middle East countries: a systematic review of the literature. European Journal of Clinical Pharmacology, 69(4), https://doi.org/10.1007/s00228-012-1435-y

Background: Medication errors are a significant global concern and can cause serious medical consequences for
patients. Little is known about medication errors in Middle
Eastern countries. The objectives of this systematic review
were to review st... Read More about Medication errors in the Middle East countries: a systematic review of the literature.