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Outputs (7)

Magnetoencephalography abnormalities in adult mild traumatic brain injury: A systematic review (2021)
Journal Article
Allen, C. M., Halsey, L., Topcu, G., Rier, L., Gascoyne, L. E., Scadding, J. W., Furlong, P. L., Dunkley, B. T., das Nair, R., Brookes, M. J., & Evangelou, N. (2021). Magnetoencephalography abnormalities in adult mild traumatic brain injury: A systematic review. NeuroImage: Clinical, 31, Article 102697. https://doi.org/10.1016/j.nicl.2021.102697

Background: The global incidence of traumatic brain injuries is rising, with at least 80% being classified as mild. These mild injuries are not visible on routine clinical imaging. The potential clinical role of a specific imaging biomarker be it dia... Read More about Magnetoencephalography abnormalities in adult mild traumatic brain injury: A systematic review.

Motor-related oscillatory activity in schizophrenia according to phase of illness and clinical symptom severity (2020)
Journal Article
Gascoyne, L. E., Brookes, M. J., Rathnaiah, M., Zia Ul Haq Katshu, M., Koelewijn, L., Williams, G., Kumar, J., Walters, J. T., Seedat, Z. A., Palaniyappan, L., William Deakin, J., Singh, K. D., Liddle, P. F., & Morris, P. G. (2021). Motor-related oscillatory activity in schizophrenia according to phase of illness and clinical symptom severity. NeuroImage: Clinical, 29, Article 102524. https://doi.org/10.1016/j.nicl.2020.102524

Magnetoencephalography (MEG) measures magnetic fields generated by synchronised neural current flow and provides direct inference on brain electrophysiology and connectivity, with high spatial and temporal resolution. The movement-related beta decrea... Read More about Motor-related oscillatory activity in schizophrenia according to phase of illness and clinical symptom severity.

Quantifying the core deficit in classical schizophrenia (2020)
Journal Article
Rathnaiah, M., Liddle, E., Gascoyne, L., Kumar, J., Zia Ul Haq Katshu, M., Faruqi, C., Kelly, C., Gill, M., Robson, S., Brookes, M., Palaniyappan, L., Morris, P., & Liddle, P. F. (2020). Quantifying the core deficit in classical schizophrenia. Schizophrenia Bulletin Open, 1(1), Article sgaa031. https://doi.org/10.1093/schizbullopen/sgaa031

In the classical descriptions of schizophrenia, Kraepelin and Bleuler recognised disorganization and impoverishment of mental activity as fundamental symptoms. Their classical descriptions also included a tendency to persisting disability. The psycho... Read More about Quantifying the core deficit in classical schizophrenia.

Glutathione and glutamate in schizophrenia: a 7T MRS study (2018)
Journal Article
Kumar, J., Liddle, E. B., Fernandes, C. C., Palaniyappan, L., Hall, E. L., Robson, S. E., Simmonite, M., Fiesal, J., Katshu, M. Z., Qureshi, A., Skelton, M., Christodoulou, N. G., Brookes, M. J., Morris, P. G., & Liddle, P. F. (2018). Glutathione and glutamate in schizophrenia: a 7T MRS study. Molecular Psychiatry, 25(4), 873–882. https://doi.org/10.1038/s41380-018-0104-7

© 2018 The Author(s) In schizophrenia, abnormal neural metabolite concentrations may arise from cortical damage following neuroinflammatory processes implicated in acute episodes. Inflammation is associated with increased glutamate, whereas the antio... Read More about Glutathione and glutamate in schizophrenia: a 7T MRS study.

Abnormal salience signaling in schizophrenia: The role of integrative beta oscillations: Salience Signaling in Schizophrenia (2016)
Journal Article
Liddle, E. B., Price, D., Palaniyappan, L., Brookes, M. J., Robson, S. E., Hall, E. L., Morris, P. G., & Liddle, P. F. (2016). Abnormal salience signaling in schizophrenia: The role of integrative beta oscillations: Salience Signaling in Schizophrenia. Human Brain Mapping, 37(4), 1361-1374. https://doi.org/10.1002/hbm.23107

Aberrant salience attribution and cerebral dysconnectivity both have strong evidential support as core dysfunctions in schizophrenia. Aberrant salience arising from an excess of dopamine activity has been implicated in delusions and hallucinations, e... Read More about Abnormal salience signaling in schizophrenia: The role of integrative beta oscillations: Salience Signaling in Schizophrenia.

Abnormal visuomotor processing in schizophrenia (2015)
Journal Article
Robson, S. E., Brookes, M. J., Hall, E. L., Palaniyappan, L., Kumar, J., Skelton, M., Christodoulou, N. G., Qureshi, A., Jan, F., Katshu, M. Z., Liddle, E. B., Liddle, P. F., & Morris, P. G. (2016). Abnormal visuomotor processing in schizophrenia. NeuroImage: Clinical, 12, 869-878. https://doi.org/10.1016/j.nicl.2015.08.005

Subtle disturbances of visual and motor function are known features of schizophrenia and can greatly impact quality of life; however, few studies investigate these abnormalities using simple visuomotor stimuli. In healthy people, electrophysiological... Read More about Abnormal visuomotor processing in schizophrenia.